Generation of urinary steroid profiles in patients with adrenal incidentaloma using gas chromatography–mass spectrometry

L. I. Velikanova; E. G. Strel’nikova; E. V. Obedkova; N. S. Krivokhizhina; Z. R. Shafigullina; K. Grigoryan; V. G. Povarov; A. L. Moskvin

doi:10.1134/S1061934816070169

Generation of urinary steroid profiles in patients with adrenal incidentaloma using gas chromatography–mass spectrometry

Авторлар: Velikanova L.¹, Strel’nikova E.¹, Obedkova E.¹, Krivokhizhina N.¹, Shafigullina Z.¹, Grigoryan K.¹, Povarov V.², Moskvin A.²
Мекемелер:
1. Northwestern State Medical University
2. St. Petersburg State University
Шығарылым: Том 71, № 7 (2016)
Беттер: 748-754
Бөлім: Articles
URL: https://journals.rcsi.science/1061-9348/article/view/181930
DOI: https://doi.org/10.1134/S1061934816070169
ID: 181930

Дәйексөз келтіру

Толық мәтін

Ашық рұқсат
Рұқсат жабық

Рұқсат берілді
Рұқсат жабық

Тек жазылушылар үшін

Аннотация
Авторлар туралы
Әдебиет тізімі
Статистика

Аннотация

A method is developed for the determination of steroid hormones in urine using gas chromatography with mass-spectrometric detection. Sample preparation procedure and the conditions of chromatographic analysis were optimized, and characteristic urinary steroid profiles of patients with adrenocortical cancer were obtained. Criteria for the evaluation of the deficiency of 21-hydroxylase and 11β-hydroxylase in patients with adrenal incidentaloma are proposed.