Application of a Chemical Sensor Array to Assessing the Presence of Neoplasms by Blood Smell
- Authors: Kuchmenko T.A.1, Shuba A.A.1, Bityukova V.V.2, Matveeva N.A.3
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Affiliations:
- Department of Environment and Chemical Engineering
- Burdenko State Medical University
- Voronezh City Clinical Hospital no. 11
- Issue: Vol 73, No 1 (2018)
- Pages: 91-101
- Section: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182775
- DOI: https://doi.org/10.1134/S1061934817110053
- ID: 182775
Cite item
Abstract
The results of using a piezosensor array for assessing the presence of benign and malignant neoplasms in gynecologic patients by the presence and concentration of marker gases in the headspace of blood samples are discussed. With the help of identification parameters of the sensor array, marker gases of the investigated pathological processes were detected in the headspace of blood samples, and the features of their composition depending on the type of tumor were determined. A model was developed using partial least squares regression to obtain fast screening information (sick/healthy) from the results of adsorption of headspace of blood samples. The correctness, sensitivity, and specificity of the proposed approach to the detection of marker gases in the headspace of blood samples using an array of chemical sensors are estimated.
Keywords
About the authors
T. A. Kuchmenko
Department of Environment and Chemical Engineering
Email: an-mishina@yandex.ru
Russian Federation, Voronezh, 394000
A. A. Shuba
Department of Environment and Chemical Engineering
Author for correspondence.
Email: an-mishina@yandex.ru
Russian Federation, Voronezh, 394000
V. V. Bityukova
Burdenko State Medical University
Email: an-mishina@yandex.ru
Russian Federation, Voronezh, 394000
N. A. Matveeva
Voronezh City Clinical Hospital no. 11
Email: an-mishina@yandex.ru
Russian Federation, Voronezh, 394042