Application of a Chemical Sensor Array to Assessing the Presence of Neoplasms by Blood Smell

Abstract

The results of using a piezosensor array for assessing the presence of benign and malignant neoplasms in gynecologic patients by the presence and concentration of marker gases in the headspace of blood samples are discussed. With the help of identification parameters of the sensor array, marker gases of the investigated pathological processes were detected in the headspace of blood samples, and the features of their composition depending on the type of tumor were determined. A model was developed using partial least squares regression to obtain fast screening information (sick/healthy) from the results of adsorption of headspace of blood samples. The correctness, sensitivity, and specificity of the proposed approach to the detection of marker gases in the headspace of blood samples using an array of chemical sensors are estimated.