Exploration of antioxidant activity of newly synthesized azo flavones and its correlation with electrochemical parameters along with the study of their redox behaviour


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Аннотация

A series of 7-hydroxy-2-aryl-3-(2-aryldiazenyl)-4H-chromen-4-one derivatives was synthesized in quantitative yields. Herein, we demonstrate the antioxidant potential of the synthesized substituted azo flavones using 1,1-diphenyl-2-picryl-hydrazyl assay method along with the evaluation of their redox behaviour by cyclic voltammetry. The synthesized compounds manifested good antioxidant potential as compared to standard antioxidant ascorbic acid, which especially pertains to the compounds having methoxy and hydroxyl groups. A good correlation between minimum inhibitory concentration (IC50) and deduced electrochemical parameter, i.e., half peak oxidation potential (Ep/2) values, was established.

Авторлар туралы

A. Kumar

School of Chemical Sciences

Хат алмасуға жауапты Автор.
Email: drashoksharma2001@yahoo.com
Үндістан, Khandwa Road, Indore, M.P., 452 001

P. Sharma

School of Chemical Sciences

Email: drashoksharma2001@yahoo.com
Үндістан, Khandwa Road, Indore, M.P., 452 001

P. Sharma

School of Chemical Sciences

Email: drashoksharma2001@yahoo.com
Үндістан, Khandwa Road, Indore, M.P., 452 001

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