Exploration of antioxidant activity of newly synthesized azo flavones and its correlation with electrochemical parameters along with the study of their redox behaviour
- Authors: Kumar A.1, Sharma P.1, Sharma P.K.1
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Affiliations:
- School of Chemical Sciences
- Issue: Vol 72, No 10 (2017)
- Pages: 1034-1044
- Section: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182640
- DOI: https://doi.org/10.1134/S1061934817100094
- ID: 182640
Cite item
Abstract
A series of 7-hydroxy-2-aryl-3-(2-aryldiazenyl)-4H-chromen-4-one derivatives was synthesized in quantitative yields. Herein, we demonstrate the antioxidant potential of the synthesized substituted azo flavones using 1,1-diphenyl-2-picryl-hydrazyl assay method along with the evaluation of their redox behaviour by cyclic voltammetry. The synthesized compounds manifested good antioxidant potential as compared to standard antioxidant ascorbic acid, which especially pertains to the compounds having methoxy and hydroxyl groups. A good correlation between minimum inhibitory concentration (IC50) and deduced electrochemical parameter, i.e., half peak oxidation potential (Ep/2) values, was established.
About the authors
A. Kumar
School of Chemical Sciences
Author for correspondence.
Email: drashoksharma2001@yahoo.com
India, Khandwa Road, Indore, M.P., 452 001
P. Sharma
School of Chemical Sciences
Email: drashoksharma2001@yahoo.com
India, Khandwa Road, Indore, M.P., 452 001
P. K. Sharma
School of Chemical Sciences
Email: drashoksharma2001@yahoo.com
India, Khandwa Road, Indore, M.P., 452 001