Email this article Mechanism of reaction of selenium elimination in diacetophenonyl selenide under the action of reduced glutathione
- Authors: Poluboyarinov P.A.1, Leshchenko P.P.1, Moiseeva I.Y.2, Kolesnikova S.G.3, Epshtein N.B.3
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Affiliations:
- Penza State University of Architecture and Construction
- Penza State University
- National Research Nuclear University MEPhI
- Issue: Vol 72, No 7 (2017)
- Pages: 739-744
- Section: Articles
- URL: https://journals.rcsi.science/1061-9348/article/view/182544
- DOI: https://doi.org/10.1134/S1061934817070103
- ID: 182544
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Abstract
Products of reaction between the organoselenium xenobiotic, diacetophenonyl selenide (1,5-diphenyl-3-selenapenta-1,5-dione), and reduced glutathione at different molar ratios and pH values were studied by HPLC and TLC. Reaction intermediates, S-(acetophenylselenyl)glutathione and glutathione selenodisulfide, and reaction products, acetophenone and hydroselenide anion, were detected. The reaction scheme proposed earlier was confirmed.
About the authors
P. A. Poluboyarinov
Penza State University of Architecture and Construction
Author for correspondence.
Email: poluboyarinovpavel@yandex.ru
Russian Federation, Penza, 440028
P. P. Leshchenko
Penza State University of Architecture and Construction
Email: poluboyarinovpavel@yandex.ru
Russian Federation, Penza, 440028
I. Ya. Moiseeva
Penza State University
Email: poluboyarinovpavel@yandex.ru
Russian Federation, Penza, 440026
S. G. Kolesnikova
National Research Nuclear University MEPhI
Email: poluboyarinovpavel@yandex.ru
Russian Federation, Obninsk, 249040
N. B. Epshtein
National Research Nuclear University MEPhI
Email: poluboyarinovpavel@yandex.ru
Russian Federation, Obninsk, 249040
