Methods of determination of sulfur yperite–DNA adducts


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Resumo

A review of publications on methods for the determination of sulfur yperite adducts with DNA in different biological samples (whole blood, urine, organ and tissue homogenates) is presented. Methods of formation and structures of the most important adducts are considered. Methods of the isolation and hydrolysis of adducts with DNA from biological samples are summarized.

Sobre autores

O. Orlova

Scientific Research Institute of Hygiene, Professional Pathology, and Human Ecology

Autor responsável pela correspondência
Email: orlolga@yandex.ru
Rússia, st. Kapitolovo, Leningrad oblast, 188663

E. Savel’eva

Scientific Research Institute of Hygiene, Professional Pathology, and Human Ecology

Email: orlolga@yandex.ru
Rússia, st. Kapitolovo, Leningrad oblast, 188663

G. Karakashev

Scientific Research Institute of Hygiene, Professional Pathology, and Human Ecology

Email: orlolga@yandex.ru
Rússia, st. Kapitolovo, Leningrad oblast, 188663

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