Email this article Methods of determination of sulfur yperite–DNA adducts
- Authors: Orlova O.I.1, Savel’eva E.I.1, Karakashev G.V.1
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Affiliations:
- Scientific Research Institute of Hygiene, Professional Pathology, and Human Ecology
- Issue: Vol 72, No 3 (2017)
- Pages: 256-263
- Section: Reviews
- URL: https://journals.rcsi.science/1061-9348/article/view/182331
- DOI: https://doi.org/10.1134/S1061934817010099
- ID: 182331
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Abstract
A review of publications on methods for the determination of sulfur yperite adducts with DNA in different biological samples (whole blood, urine, organ and tissue homogenates) is presented. Methods of formation and structures of the most important adducts are considered. Methods of the isolation and hydrolysis of adducts with DNA from biological samples are summarized.
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About the authors
O. I. Orlova
Scientific Research Institute of Hygiene, Professional Pathology, and Human Ecology
Author for correspondence.
Email: orlolga@yandex.ru
Russian Federation, st. Kapitolovo, Leningrad oblast, 188663
E. I. Savel’eva
Scientific Research Institute of Hygiene, Professional Pathology, and Human Ecology
Email: orlolga@yandex.ru
Russian Federation, st. Kapitolovo, Leningrad oblast, 188663
G. V. Karakashev
Scientific Research Institute of Hygiene, Professional Pathology, and Human Ecology
Email: orlolga@yandex.ru
Russian Federation, st. Kapitolovo, Leningrad oblast, 188663
