Methods of determination of sulfur yperite–DNA adducts


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A review of publications on methods for the determination of sulfur yperite adducts with DNA in different biological samples (whole blood, urine, organ and tissue homogenates) is presented. Methods of formation and structures of the most important adducts are considered. Methods of the isolation and hydrolysis of adducts with DNA from biological samples are summarized.

作者简介

O. Orlova

Scientific Research Institute of Hygiene, Professional Pathology, and Human Ecology

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Email: orlolga@yandex.ru
俄罗斯联邦, st. Kapitolovo, Leningrad oblast, 188663

E. Savel’eva

Scientific Research Institute of Hygiene, Professional Pathology, and Human Ecology

Email: orlolga@yandex.ru
俄罗斯联邦, st. Kapitolovo, Leningrad oblast, 188663

G. Karakashev

Scientific Research Institute of Hygiene, Professional Pathology, and Human Ecology

Email: orlolga@yandex.ru
俄罗斯联邦, st. Kapitolovo, Leningrad oblast, 188663


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