Mutational landscape of prostate tumors revealed by whole-exome sequencing
- 作者: Gilyazova I.1,2, Yankina M.2, Kunsbaeva G.1, Klimentova E.2, Izmaylov A.3, Pavlov V.3, Khusnutdinova E.1,2
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隶属关系:
- Department of Genetics and Medicine
- Institute of Biochemistry and Genetics, Ufa Research Center
- Department of Urology
- 期: 卷 52, 编号 9 (2016)
- 页面: 999-1003
- 栏目: Short Communications
- URL: https://journals.rcsi.science/1022-7954/article/view/187902
- DOI: https://doi.org/10.1134/S1022795416090052
- ID: 187902
如何引用文章
详细
The results of the whole-exome DNA sequencing of eight prostate adenocarcinoma patients are presented. DNA was isolated from the peripheral blood as well as healthy and tumor prostate tissue from each patient. Bioinformatics analysis was conducted and the most significant mutations in prostate cancer patients were revealed. The obtained data could be important for understanding of the molecular mechanisms of prostate cancer pathogenesis and facilitate development of new approaches for treatment of the disease.
作者简介
I. Gilyazova
Department of Genetics and Medicine; Institute of Biochemistry and Genetics, Ufa Research Center
编辑信件的主要联系方式.
Email: gilyasova_irina@mail.ru
俄罗斯联邦, Ufa, 450074; Ufa, 450054
M. Yankina
Institute of Biochemistry and Genetics, Ufa Research Center
Email: gilyasova_irina@mail.ru
俄罗斯联邦, Ufa, 450054
G. Kunsbaeva
Department of Genetics and Medicine
Email: gilyasova_irina@mail.ru
俄罗斯联邦, Ufa, 450074
E. Klimentova
Institute of Biochemistry and Genetics, Ufa Research Center
Email: gilyasova_irina@mail.ru
俄罗斯联邦, Ufa, 450054
A. Izmaylov
Department of Urology
Email: gilyasova_irina@mail.ru
俄罗斯联邦, Ufa, 450000
V. Pavlov
Department of Urology
Email: gilyasova_irina@mail.ru
俄罗斯联邦, Ufa, 450000
E. Khusnutdinova
Department of Genetics and Medicine; Institute of Biochemistry and Genetics, Ufa Research Center
Email: gilyasova_irina@mail.ru
俄罗斯联邦, Ufa, 450074; Ufa, 450054