Email this article Antibiotic resistance genes in pathogens of open cavities
- Authors: Shabunin S.V.1, Vostroilova G.A.1, Shabanov D.I.1, Burakova I.Y.2, Smirnova Y.D.2, Gryaznova M.V.2, Syromyatnikov M.Y.1,2
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Affiliations:
- All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy
- Voronezh State University of Engineering Technologies
- Issue: Vol 94, No 1 (2024)
- Pages: 25-31
- Section: С КАФЕДРЫ ПРЕЗИДИУМА РАН
- URL: https://journals.rcsi.science/0869-5873/article/view/258765
- DOI: https://doi.org/10.31857/S0869587324010055
- EDN: https://elibrary.ru/HAYQAL
- ID: 258765
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Abstract
The work is devoted to the study of the phenotypic and genotypic resistance to antibiotics of bacteria that cause diseases of open cavities of farm animals – mastitis and colibacteriosis. A high prevalence of antibiotic resistance genes of bacteria has been established, both in the gut of piglets and in the causative agents of cow mastitis. It is noteworthy that 38% of the identified genes in the gut microbiota were beta-lactam antibiotic resistance genes. It has been shown that all bacteria E. coli of piglets’ gut turned out to be phenotypically multiresistant. More than 88% of the causative agents of mastitis in cows were characterized by resistance to benzylpenicillin, ampicillin, lincomycin and polymyxin. At the same time, 19 varieties of antibiotic resistance genes have been identified in the causative agents of mastitis.
The study of phenotypic resistance to antibiotics and the genome of pathogens of farm animals did not reveal stable correlations between them. It is necessary to conduct further active research in the field of circulation of resistance genes in livestock farms for the safety of livestock.
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About the authors
S. V. Shabunin
All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy
Author for correspondence.
Email: vnivipat@mail.ru
академик РАН, научный руководитель ВНИВИПФиТ
Russian Federation, VoronezhG. A. Vostroilova
All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy
Email: gvostroilova@mail.ru
доктор биологических наук, заведующая лабораторией доклинических исследований и моделирования биологических систем ВНИВИПФиТ
Russian Federation, VoronezhD. I. Shabanov
All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy
Email: am7d@mail.ru
научный сотрудник лаборатории доклинических исследований и моделирования биологических систем ВНИВИПФиТ
Russian Federation, VoronezhI. Y. Burakova
Voronezh State University of Engineering Technologies
Email: vitkalovai@inbox.ru
младший научный сотрудник ВГУИТ
Russian Federation, VoronezhYu. D. Smirnova
Voronezh State University of Engineering Technologies
Email: dyd16@mail.ru
младший научный сотрудник ВГУИТ
Russian Federation, VoronezhM. V. Gryaznova
Voronezh State University of Engineering Technologies
Email: mariya-vg@mail.ru
младший научный сотрудник ВГУИТ
Russian Federation, VoronezhM. Y. Syromyatnikov
All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy; Voronezh State University of Engineering Technologies
Email: syromyatnikov@bio.vsu.ru
кандидат биологических наук, ведущий научный сотрудник ВГУИТ
Russian Federation, Voronezh; VoronezhReferences
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