Antibiotic resistance genes in pathogens of open cavities

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The work is devoted to the study of the phenotypic and genotypic resistance to antibiotics of bacteria that cause diseases of open cavities of farm animals – mastitis and colibacteriosis. A high prevalence of antibiotic resistance genes of bacteria has been established, both in the gut of piglets and in the causative agents of cow mastitis. It is noteworthy that 38% of the identified genes in the gut microbiota were beta-lactam antibiotic resistance genes. It has been shown that all bacteria E. coli of piglets’ gut turned out to be phenotypically multiresistant. More than 88% of the causative agents of mastitis in cows were characterized by resistance to benzylpenicillin, ampicillin, lincomycin and polymyxin. At the same time, 19 varieties of antibiotic resistance genes have been identified in the causative agents of mastitis.

The study of phenotypic resistance to antibiotics and the genome of pathogens of farm animals did not reveal stable correlations between them. It is necessary to conduct further active research in the field of circulation of resistance genes in livestock farms for the safety of livestock.

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作者简介

S. Shabunin

All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy

编辑信件的主要联系方式.
Email: vnivipat@mail.ru

академик РАН, научный руководитель ВНИВИПФиТ

俄罗斯联邦, Voronezh

G. Vostroilova

All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy

Email: gvostroilova@mail.ru

доктор биологических наук, заведующая лабораторией доклинических исследований и моделирования биологических систем ВНИВИПФиТ

俄罗斯联邦, Voronezh

D. Shabanov

All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy

Email: am7d@mail.ru

научный сотрудник лаборатории доклинических исследований и моделирования биологических систем ВНИВИПФиТ

俄罗斯联邦, Voronezh

I. Burakova

Voronezh State University of Engineering Technologies

Email: vitkalovai@inbox.ru

младший научный сотрудник ВГУИТ

俄罗斯联邦, Voronezh

Yu. Smirnova

Voronezh State University of Engineering Technologies

Email: dyd16@mail.ru

младший научный сотрудник ВГУИТ

俄罗斯联邦, Voronezh

M. Gryaznova

Voronezh State University of Engineering Technologies

Email: mariya-vg@mail.ru

младший научный сотрудник ВГУИТ

俄罗斯联邦, Voronezh

M. Syromyatnikov

All-Russian Veterinary Research Institute of Pathology, Pharmacology and Therapy; Voronezh State University of Engineering Technologies

Email: syromyatnikov@bio.vsu.ru

кандидат биологических наук, ведущий научный сотрудник ВГУИТ

俄罗斯联邦, Voronezh; Voronezh

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2. Fig. 1. Phenotypic resistance of bacteria causing mastitis in cows

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