The Potential of Using Genetically Characterized Human Biomaterial in Reproduction

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Abstract

Modern achievements in the field of genomic medicine and biobanking open up new prospects for improving reproductive medicine. The integration of high-performance genetic technologies with biobanking systems for the storage of biological samples makes it possible to fundamentally change approaches to the prediction and prevention of reproductive pathologies. The key advantage of such an integrative approach is the possibility of conducting a large-scale analysis of genetic risks at the population level, followed by the development of personalized preventive strategies, such as the creation of complex genetic panels for preconceptional screening of hereditary pathologies, the improvement of algorithms for predicting reproductive complications based on multifactorial analysis, and the development of test systems and drugs for targeted therapy.

About the authors

A. A Basipova (Mikhailova)

D.O. Ott Scientific Research Institute of Obstetrics, Gynecology and Reproductology

Email: anamikhailova@gmail.com
ORCID iD: 0000-0002-5020-9561
Department of Genomic Medicine Saint Petersburg, Russian Federation

Y. A Nasykhova

D.O. Ott Scientific Research Institute of Obstetrics, Gynecology and Reproductology

Email: yulnasa@gmail.com
ORCID iD: 0000-0002-3543-4963
Department of Genomic Medicine Saint Petersburg, Russian Federation

A. S Glotov

D.O. Ott Scientific Research Institute of Obstetrics, Gynecology and Reproductology

Email: anglotov@mail.ru
ORCID iD: 0000-0002-0091-2224
Department of Genomic Medicine Saint Petersburg, Russian Federation

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