Heat shock proteins on the surface of tumor cells as a target for anti-tumor therapy
- 作者: Makarova A.1,2, Kostenko V.1,2, Ovsyanikova O.1,2, Svirshchevskaya E.1, Lutsenko G.1, Sapozhnikov A.1
-
隶属关系:
- Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS
- Lomonosov Moscow State University
- 期: 卷 50, 编号 3 (2024)
- 页面: 218-230
- 栏目: Articles
- URL: https://journals.rcsi.science/0132-3423/article/view/261462
- DOI: https://doi.org/10.31857/S0132342324030027
- EDN: https://elibrary.ru/OAKNVU
- ID: 261462
如何引用文章
详细
According to WHO, oncological diseases are the cause of ~5 million people deaths annually. To date, there is no universal solution to fight cancer, despite outstanding achievements in the field of radiotherapy, chemotherapy, and immunotherapy. In this regard, there is a need to develop new approaches to antitumor therapy, in particular based on the search and use of targeted molecules that allow killing tumor cells of various types with high efficiency, without significant toxic effects on healthy organs and tissues. This review presents the characteristics of the main heat shock protein (HSP) families, the features of their expression in tumor cells and the possibility of using monoclonal antibodies to these proteins as a guiding vector for antitumor immunotherapy.
全文:
作者简介
A. Makarova
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS; Lomonosov Moscow State University
Email: amsap@mail.ru
俄罗斯联邦, ul. Miklukho-Maklaya 16/10, Moscow, 117997; Leninskie Gory 1, Moscow, 119991
V. Kostenko
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS; Lomonosov Moscow State University
Email: amsap@mail.ru
俄罗斯联邦, ul. Miklukho-Maklaya 16/10, Moscow, 117997; Leninskie Gory 1, Moscow, 119991
O. Ovsyanikova
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS; Lomonosov Moscow State University
Email: amsap@mail.ru
俄罗斯联邦, ul. Miklukho-Maklaya 16/10, Moscow, 117997; Leninskie Gory 1, Moscow, 119991
E. Svirshchevskaya
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS
Email: amsap@mail.ru
俄罗斯联邦, ul. Miklukho-Maklaya 16/10, Moscow, 117997
G. Lutsenko
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS
Email: amsap@mail.ru
俄罗斯联邦, ul. Miklukho-Maklaya 16/10, Moscow, 117997
A. Sapozhnikov
Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry RAS
编辑信件的主要联系方式.
Email: amsap@mail.ru
俄罗斯联邦, ul. Miklukho-Maklaya 16/10, Moscow, 117997
参考
- Fu Z., Li S., Han S., Shi C., Zhang Y. // Signal Transduct. Target Ther. 2022. V. 7. P. 93. https://doi.org/10.1038/s41392-022-00947-7
- Beck A., Goetsch L., Dumontet C., Corvaïa N. // Nat. Rev. Drug. Discov. 2017. V. 16. P. 315–337. https://doi.org/10.1038/nrd.2016.268
- Richter K., Haslbeck M., Buchner J. // Mol. Cell. 2010. V. 40. P. 253–266. https://doi.org/10.1016/j.molcel.2010.10.006
- Mertz-Henning L.M., Pegoraro C., Maia L.C., Venske E., Rombaldi C.V., Costa de Oliveira A. // Genet. Mol. Res. 2016. V. 15. P. gmr.15027954. https://doi.org/10.4238/gmr.15027954
- Cedraz H., Gromboni J.G.G., Garcia A.A.P., Jr., Farias Filho R.V., Souza T.M., Oliveira E.R., Oliveira E.B., Nascimento C.S.D., Meneghetti C., Wenceslau A.A. // PLoS One. 2017. V. 12. P. e0186083. https://doi.org/10.1371/journal.pone.0186083
- Taha E.A., Ono K., Eguchi T.// Int. J. Mol. Sci. 2019. V. 20. P. 4588. https://doi.org/10.3390/ijms20184588
- García Lorenzo J., León Vintró X., Camacho Pérez de Madrid M. // Acta Otorrinolaringol. Esp. 2016. V. 67. P. 130–134. https://doi.org/10.1016/j.otorri.2015.03.002
- Minnaar C.A., Szasz A. // Cells. 2022. V. 11. P. 1838. https://doi.org/10.3390/cells11111838
- Youness R.A., Gohar A., Kiriacos C.J., El-Shazly M. // Adv. Exp. Med. Biol. 2023. V. 1409. P. 193–203. https://doi.org/10.1007/5584_2022_736
- Lianos G.D., Alexiou G.A., Mangano A., Mangano A., Rausei S., Boni L., Dionigi G., Roukos D.H.// Cancer Lett. 2015. V. 360. P. 114–118. https://doi.org/10.1016/j.canlet.2015.02.026
- Wu J., Liu T., Rios Z., Mei Q., Lin X., Cao S. // Trends Pharmacol. Sci. 2017. V. 38. P. 226–256. https://doi.org/10.1016/j.tips.2016.11.009
- Yun C.W., Kim H.J., Lim J.H., Lee S.H. // Cells. 2019. V. 9. P. 60. https://doi.org/10.3390/cells9010060
- Fernández-Fernández M.R., GrageraM., OchoaIbarrola L., Quintana-Gallardo L., Valpuesta J.M. // FEBS Lett. 2017. V. 591. P. 2648–2660. https://doi.org/10.1002/1873-3468.12751
- Havalová H., Ondrovičová G., Keresztesová B., Bauer J.A., Pevala V., Kutejová E., Kunová N. // Int. J. Mol. Sci. 2021. V. 22. P. 8077. https://doi.org/10.3390/ijms22158077
- Stangl S., Gehrmann M., Riegger J., Kuhs K., Riederer I., Sievert W., Hube K., Mocikat R., Dressel R., Kremmer E., Pockley A.G., Friedrich L., Vigh L., Skerra A., Multhoff G. // Proc. Natl. Acad. Sci. USA. 2011. V. 108. P. 733–738. https://doi.org/10.1073/pnas.1016065108
- Liu Q., Liang C., Zhou L. // Protein Sci. 2020. V. 29. P. 378–390. https://doi.org/10.1002/pro.3725
- Fan W., Fan S.S., Feng J., Xiao D., Fan S., Luo J. // PLoS One. 2017. V. 12. P. e0185563. https://doi.org/10.1371/journal.pone.0185563
- Shiber A., Ravid T. // Biomolecules. 2014. V. 4. P. 704– 724. https://doi.org/10.3390/biom4030704
- Werner C., Stangl S., Salvermoser L., Schwab M., Shevtsov M., Xanthopoulos A., Wang F., Dezfouli A.B., Thölke D., Ostheimer C., Medenwald D., Windberg M., Bache M., Schlapschy M., Skerra A., Multhoff G. // Cancers. 2021. V. 13. P. 3706. https://doi.org/10.3390/cancers13153706
- Zolkiewski M., Zhang T., Nagy M. // Arch. Biochem. Biophys. 2012. V. 520. P. 1–6. https://doi.org/10.1016/j.abb.2012.01.012
- Wang X.Y., Subjeck J.R. // Int. J. Hyperthermia. 2013. V. 29. P. 364–375. https://doi.org/10.3109/02656736.2013.803607
- Hightower L.E., Guidon P.T., Jr. // J. Cell Physiol. 1989. V. 138. P. 257–266. https://doi.org/10.1002/jcp.1041380206
- Mambula S.S., Calderwood S.K. // J. Immunol. 2006. V. 177. P. 7849–7857. https://doi.org/10.4049/jimmunol.177.11.7849
- Li D.Y., Liang S., Wen J.H., Tang J.X., Deng S.L., Liu Y.X. // Molecules. 2022. V. 27. P. 2361. https://doi.org/10.3390/molecules27072361
- Broquet A.H., Thomas G., Masliah J., Trugnan G., Bachelet M. // J. Biol. Chem. 2003. V. 278. P. 21601– 21606. https://doi.org/10.1074/jbc.M302326200
- Gehrmann M., Liebisch G., Schmitz G., Anderson R., Steinem C., De Maio A., Pockley G., Multhoff G. // PLoS One. 2008. V. 3. P. e1925. https://doi.org/10.1371/journal.pone.0001925
- Bilog A.D., Smulders L., Oliverio R., Labanieh C., Zapanta J., Stahelin R.V., Nikolaidis N. // Biomolecules. 2019. V. 9. P. 152. https://doi.org/10.3390/biom9040152
- Pomorski T., Holthuis J.C., Herrmann A., van Meer G. // J. Cell Sci. 2004. V. 117. P. 805–813. https://doi.org/10.1242/jcs.01055
- Schilling D., Gehrmann M., Steinem C., De Maio A., Pockley A.G., Abend M., Molls M., Multhoff G. // FASEB J. 2009. V. 23. P. 2467–2477. https://doi.org/10.1096/fj.08-125229
- Shevtsov M.A., Komarova E.Y., Meshalkina D.A., Bychkova N.V., Aksenov N.D., Abkin S.V., Margulis B.A., Guzhova I.V. // Oncotarget. 2014. V. 5. P. 3101–3114. https://doi.org/10.18632/oncotarget.1820
- Benaroudj N., Ebel C., Ladjimi M.M. // Eur. J. Biochem. 1999. V. 259. P. 379–384. https://doi.org/10.1046/j.1432-1327.1999.00053.x
- Rafiee M., Kanwar J.R., Berg R.W., Lehnert K., Lisowska K., Krissansen G.W. // Cancer Gene Ther. 2001. V. 8. P. 974–981. https://doi.org/10.1038/sj.cgt.7700395
- Bethke K., Staib F., Distler M., Schmitt U., Jonuleit H., Enk A.H., Galle P.R., Heike M. // J. Immunol. 2002. V. 169. P. 6141–6148. https://doi.org/10.4049/jimmunol.169.11.6141
- Luo H., Yang H., Lin Y., Zhang Y., Pan C., Feng P., Yu Y., Chen X. // Oncotarget. 2017. V. 8. P. 98455–98470. https://doi.org/10.18632/oncotarget.21427
- Yurinskaya M.M., Kochetkova O.Y., Shabarchina L.I., Antonova O.Y., Suslikov A.V., Evgen’ev M.B., Vinokurov M.G. // Cell Stress Chaperones. 2017. V. 22. P. 163–171. https://doi.org/10.1007/s12192-016-0743-z
- Evgen’ev M.B. // Cell Stress Chaperones. 2021. V. 26. P. 617–627. https://doi.org/10.1007/s12192-021-01219-z
- Komarova E.Y., Marchenko L.V., Zhakhov A.V., Nikotina A.D., Aksenov N.D., Suezov R.V., Ischenko A.M., Margulis B.A., Guzhova I.V. // Int. J. Mol. Sci. 2019. V. 21. P. 59–77. https://doi.org/10.3390/ijms21010059
- Shevtsov M.A., Pozdnyakov A.V., Mikhrina A.L., Yakovleva L.Y., Nikolaev B.P., Dobrodumov A.V., Meshalkina D.A., Ischenko A.M., Pitkin E., Guzhova I.V., Margulis B.A. // Int. J. Cancer. 2014. V. 135. P. 2118–2128. https://doi.org/10.1002/ijc.28858
- Lobinger D., Gempt J., Sievert W., Barz M., Schmitt S., Nguyen H.T., Stangl S., Werner C., Wang F., Wu Z., Fan H., Zanth H., Shevtsov M., Pilz M., Riederer I., Schwab M., Schlegel J., Multhoff G. // Front. Mol. Biosci. 2021. V. 8. P. 669366. https://doi.org/10.3389/fmolb.2021.669366
- Krause S.W., Gastpar R., Andreesen R., Gross C., Ullrich H., Thonigs G., Pfister K., Multhoff G. // Clin. Cancer Res. 2004. V. 10. P. 3699–3707. https://doi.org/10.1158/1078-0432.CCR-03-0683
- Kaczmarek M., Lagiedo M., Masztalerz A., Kozlowska M., Nowicka A., Brajer B., Batura-Gabryel H., Sikora J. // Immunobiology. 2018. V. 223. P. 200–209. https://doi.org/10.1016/j.imbio.2017.10.025
- Tukaj S., Sitko K. // Biomolecules. 2022. V. 12. P. 1153. https://doi.org/10.3390/biom12081153
- Wachstein J., Tischer S., Figueiredo C., Limbourg A., Falk C., Immenschuh S., Blasczyk R., Eiz-Vesper B. // PLoS One. 2012. V. 7. P. e51747. https://doi.org/10.1371/journal.pone.0051747
- Botzler C., Li G., Issels R.D., Multhoff G. // Cell Stress Chaperones. 1998. V. 3. P. 6–11. https://doi.org/10.1379/1466-1268(1998)003<0006: doeleo>2.3.co;2
- Affatigato L., Licciardi M., Bonamore A., Martorana A., Incocciati A., Boffi A., Militello V. // Molecules. 2023. V. 28. P. 1163. https://doi.org/10.3390/molecules28031163
- Shevtsov M., Huile G., Multhoff G. // Philos. Trans. R Soc. Lond. B Biol. Sci. 2018. V. 373. P. 20160526. https://doi.org/10.1098/rstb.2016.0526
- Shevtsov M.A., Nikolaev B.P., Ryzhov V.A., Yakovleva L.Y., Marchenko Y.Y., Parr M.A., Rolich V.I., Mikhrina A.L., Dobrodumov A.V., Pitkin E., Multhoff G. // Nanoscale. 2015. V. 7. P. 20652–20664. https://doi.org/10.1039/c5nr06521f
- Shaterabadi Z., Nabiyouni G., Soleymani M. // Prog. Biophys. Mol. Biol. 2018. V. 133. P. 9–19. https://doi.org/10.1016/j.pbiomolbio.2017.10.001
- Johannsen M., Thiesen B., Wust P., Jordan A. // Int. J. Hyperthermia. 2010. V. 26. P. 790–795. https://doi.org/10.3109/02656731003745740
- Maier-Hauff K., Ulrich F., Nestler D., Niehoff H., Wust P., Thiesen B., Orawa H., Budach V., Jordan A. // J. Neurooncol. 2011. V. 103. P. 317–324. https://doi.org/10.1007/s11060-010-0389-0
- Ruan S., Yuan M., Zhang L., Hu G., Chen J., Cun X., Zhang Q., Yang Y., He Q., Gao H. // Biomaterials. 2015. V. 37. P. 425–435. https://doi.org/10.1016/j.biomaterials.2014.10.007
- Ruan S., He Q., Gao H.// Nanoscale. 2015. V. 7. P. 9487–9496. https://doi.org/10.1039/c5nr01408e
- Gehrmann M.K., Kimm M.A., Stangl S., Schmid T.E., Noël P.B., Rummeny E.J., Multhoff G. // Int. J. Nanomedicine. 2015. V. 10. P. 5687–5700. https://doi.org/10.2147/IJN.S87174
- Zheng Y., Hunting D.J., Ayotte P., Sanche L. // Radiat. Res. 2008. V. 169. P. 19–27. https://doi.org/10.1667/RR1080.1
- Schuemann J., Berbeco R.I., Chithrani D.B., Cho S.H., Kumar R.R., McMahon S.J., Sridhar S., Krishnan S. // Int. J. Radiat. Oncol. Biol. Phys. 2016. V. 94. P. 189– 205. https://doi.org/10.1016/j.ijrobp.2015.09.032
- Ali M.R., Ali H.R., Rankin C.R., El-Sayed M.A. // Biomaterials. 2016. V. 102. P. 1–8. https://doi.org/10.1016/j.biomaterials.2016.06.017
- Gehrmann M., Stangl S., Foulds G.A., Oellinger R., Breuninger S., Rad R., Pockley A.G., Multhoff G. // PLoS One. 2014. V. 9. P. 105344. https://doi.org/10.1371/journal.pone.0105344
- Poccia F., Piselli P., Di Cesare S., Bach S., Colizzi V., Mattei M., Bolognesi A., Stirpe F. // Br. J. Cancer. 1992. V. 66. P. 427–432. https://doi.org/10.1038/bjc.1992.291
- Dezfouli A.B., Stangl S., Foulds G.A., Lennartz P., Pilkington G.J., Pockley A.G., Multhoff G. // Methods Mol. Biol. 2023. V. 2693. P. 307–324. https://doi.org/10.1007/978-1-0716-3342-7_23
- Madamsetty V.S., Mukherjee A., Mukherjee S. // Front. Pharmacol. 2019. V. 10. P. 1264. https://doi.org/10.3389/fphar.2019.01264
- Slingerland M., Guchelaar H.J., Gelderblom H. // Drug Discov. Today. 2012. V. 17. P. 160–166. https://doi.org/10.1016/j.drudis.2011.09.015f
- Lu R.M., Chen M.S., Chang D.K., Chiu C.Y., Lin W.C., Yan S.L., Wang Y.P., Kuo Y.S., Yeh C.Y., Lo A., Wu H.C. // PLoS One. 2013. V. 8. P. e66128. https://doi.org/10.1371/journal.pone.0066128
- Wilhelm S., Tavares A.J., Dai Q., Ohta S., Audet J., Dvorak H.F., Chan C.W. // Nat. Rev. Mater. 2016. V. 1. P. e16014. https://doi.org/10.1038/natrevmats.2016.14
- Alswieleh A.M. // J. Chem. 2020. V. 2020. P. e9176257. https://doi.org/10.1155/2020/9176257
- Hassanpour A., Irandoust M., Soleimani E., Zhaleh H. // Mat. Sci. Eng. C Mater. Biol. Appl. 2019. V. 103. P. 109771. https://doi.org/10.1016/j.msec.2019.109771
- Lu S., Neoh K.G., Huang C., Shi Z., Kang E.T. // J. Colloid Interface Sci. 2013. V. 412. P. 46–55. https://doi.org/10.1016/j.jcis.2013.09.011
- Shevtsov M., Zhou Y., Khachatryan W., Multhoff G., Gao H. // Curr. Drug Metab. 2018. V. 19. P. 768–780. https://doi.org/10.2174/1389200219666180611080736
- Genc S., Taghizadehghalehjoughi A., Yeni Y., Jafarizad A., Hacimuftuoglu A., Nikitovic D., Docea A.O., Mezhuev Y., Tsatsakis A. // Pharmaceutics. 2023. V. 15. P. 245. https://doi.org/10.3390/pharmaceutics15010245
- Sparreboom A., Scripture C.D., Trieu V., Williams P.J., De T., Yang A., Beals B., Figg W.D., Hawkins M., Desai N. // Clin. Cancer Res. 2005. V. 11. P. 4136– 4143. https://doi.org/10.1158/1078-0432.CCR-04-2291
- Svenson S. // Chem. Soc. Rev. 2015. V. 44. P. 4131– 4144. https://doi.org/10.1039/c5cs00288e
- Caminade A.M. // J. Pers. Med. 2022. V. 12. P. 1334. https://doi.org/10.3390/jpm12081334
- Stangl S., Gehrmann M., Dressel R., Alves F., Dullin C., Themelis G., Ntziachristos V., Staeblein E., Walch A., Winkelmann I., Multhoff G. // J. Cell Mol. Med. 2011. V. 15. P. 874–887. https://doi.org/10.1111/j.1582-4934.2010.01067.x
- Multhoff G., Pfister K., Gehrmann M., Hantschel M., Gross C., Hafner M., Hiddemann W.A. // Cell Stress Chaperones. 2001. V. 6. P. 337–344. https://doi.org/10.1379/1466-1268(2001)006<0337: AMHPSN>2.0.CO;2
- Taglia L., Matusiak D., Benya R.V. // Clin. Exp. Metastasis. 2008. V. 25. P. 451–463. https://doi.org/10.1007/s10585-008-9151-9
- Gobbo J., Marcion G., Cordonnier M., Dias A.M.M., Pernet N., Hammann A., Richaud S., Mjahed H., Isambert N., Clausse V., Rébé C., Bertaut A., Goussot V., Lirussi F., Ghiringhelli F., de Thonel A., Fumoleau P., Seigneuric R., Garrido C. // J. Natl. Cancer Inst. 2015. V. 108. Р. djv330. https://doi.org/10.1093/jnci/djv330
- Schmitt E., Maingret L., Puig P.E., Rerole A.L., Ghiringhelli F., Hammann A., Solary E., Kroemer G., Garrido C. // Cancer Res. 2006. V. 66. P. 4191– 4197. https://doi.org/10.1158/0008-5472.CAN-05-3778
- McKeon A.M., Egan A., Chandanshive J., McMahon H., Griffith D.M. // Molecules. 2016. V. 21. P. 949. https://doi.org/10.3390/molecules21070949
- Adam C., Baeurle A., Brodsky J.L., Wipf P., Schrama D., Becker J.C., Houben R. // PLoS One. 2014. V. 9. P. e92041. https://doi.org/10.1371/journal.pone.0092041
- Prince T., Ackerman A., Cavanaugh A., Schreiter B., Juengst B., Andolino C., Danella J., Chernin M., Williams H. // Oncotarget. 2018. V. 9. P. 32702–32717. https://doi.org/10.18632/oncotarget.26021
- Li X., Srinivasan S.R., Connarn J., Ahmad A., Young Z.T., Kabza A.M., Zuiderweg E.R.P., Sun D., Gestwicki J.E. // ACS Med. Chem. Lett. 2013. V. 4. P. 1042–1047. https://doi.org/10.1021/ml400204n
- Wadhwa R., Sugihara T., Yoshida A., Nomura H., Reddel R.R., Simpson R., Maruta H., Kaul S.C. // Cancer Res. 2000. V. 60. P. 6818–6821.
- Koya K., Li Y., Wang H., Ukai T., Tatsuda N., Kawakami M., Shishido T., Chen L.B. // Cancer Res. 1996. V. 56. P. 538–543.
- Modica-Napolitano J.S., Koya K., Weisberg E., Brunelli B.T., Li Y., Chen L.B. // Cancer Res. 1996. V. 56. P. 544–550.
- Schett G., Xu Q., Amberger A., Van der Zee R., Recheis H., Willeit J., Wick G. // J. Clin. Invest. 1995. V. 96. P. 2569–2577. https://doi.org/10.1172/JCI118320
- Leng X., Wang X., Pang W., Zhan R., Zhang Z., Wang L., Gao X., Qian L. // Cell Stress Chaperones. 2013. V. 18. P. 483–493. https://doi.org/10.1007/s12192-013-0404-4