Synthesis and Cytotoxic Activity of Arylsubstituted Tetrazolocyclanopyrimidines
- 作者: Vasil’kova N.1, Ivonin M.1, Burygin G.2, Prilepskii A.2, Kriven’ko A.1
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隶属关系:
- N. G. Chernyshevskii Saratov State National Research University
- Institute of Plant and Microbial Biochemistry and Physiology
- 期: 卷 51, 编号 9 (2017)
- 页面: 756-759
- 栏目: The Search for New Drugs
- URL: https://journals.rcsi.science/0091-150X/article/view/244789
- DOI: https://doi.org/10.1007/s11094-017-1687-z
- ID: 244789
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详细
A series of arylsubstituted tetrazolocyclanodihydropyrimidines was prepared and their cytotoxic actions on SPEV-2 cells were studied. The activity of these substances was found to depend on the nature and position of the substitution groups in the benzene ring and the size of the alicycle. The most active compounds were o-chloro(methyl)phenyltetrazolohexahydroquinazolines.
作者简介
N. Vasil’kova
N. G. Chernyshevskii Saratov State National Research University
Email: chem@folium.ru
俄罗斯联邦, Saratov
M. Ivonin
N. G. Chernyshevskii Saratov State National Research University
Email: chem@folium.ru
俄罗斯联邦, Saratov
G. Burygin
Institute of Plant and Microbial Biochemistry and Physiology
Email: chem@folium.ru
俄罗斯联邦, Saratov
A. Prilepskii
Institute of Plant and Microbial Biochemistry and Physiology
Email: chem@folium.ru
俄罗斯联邦, Saratov
A. Kriven’ko
N. G. Chernyshevskii Saratov State National Research University
Email: chem@folium.ru
俄罗斯联邦, Saratov