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Synthesis and Cytotoxic Activity of Arylsubstituted Tetrazolocyclanopyrimidines


Дәйексөз келтіру

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Аннотация

A series of arylsubstituted tetrazolocyclanodihydropyrimidines was prepared and their cytotoxic actions on SPEV-2 cells were studied. The activity of these substances was found to depend on the nature and position of the substitution groups in the benzene ring and the size of the alicycle. The most active compounds were o-chloro(methyl)phenyltetrazolohexahydroquinazolines.

Авторлар туралы

N. Vasil’kova

N. G. Chernyshevskii Saratov State National Research University

Email: chem@folium.ru
Ресей, Saratov

M. Ivonin

N. G. Chernyshevskii Saratov State National Research University

Email: chem@folium.ru
Ресей, Saratov

G. Burygin

Institute of Plant and Microbial Biochemistry and Physiology

Email: chem@folium.ru
Ресей, Saratov

A. Prilepskii

Institute of Plant and Microbial Biochemistry and Physiology

Email: chem@folium.ru
Ресей, Saratov

A. Kriven’ko

N. G. Chernyshevskii Saratov State National Research University

Email: chem@folium.ru
Ресей, Saratov

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