Enviar artigo por via de e-mail Immobilization of Benzocaine in Polymeric Nanocontainers. Pharmacokinetic Modeling
- Autores: Shkurenko G.1, Lyrshchikov S.1, Gorlov A.1, Al’tshuler O.1,2, Al’tshuler G.1
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Afiliações:
- Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
- Kemerovo State University
- Edição: Volume 52, Nº 5 (2018)
- Páginas: 464-466
- Seção: Drug Synthesis Methods and Manufacturing Technology
- URL: https://journals.rcsi.science/0091-150X/article/view/245249
- DOI: https://doi.org/10.1007/s11094-018-1840-3
- ID: 245249
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Resumo
The possibility of immobilizing benzocaine in polymeric nanocontainers made of sulfonated cation exchangers, i.e., sulfonated polycalixarene and KU-23 30/100, was studied. The desorption kinetics of neutral and cationic benzocaine from the polymeric nanocontainers provided the desired drug-release pharmacokinetics upon peroral administration.
Sobre autores
G. Shkurenko
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
Email: altshulerh@gmail.com
Rússia, 18 Prosp. Sovetskii, Kemerovo, 650000
S. Lyrshchikov
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
Email: altshulerh@gmail.com
Rússia, 18 Prosp. Sovetskii, Kemerovo, 650000
A. Gorlov
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
Email: altshulerh@gmail.com
Rússia, 18 Prosp. Sovetskii, Kemerovo, 650000
O. Al’tshuler
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences; Kemerovo State University
Autor responsável pela correspondência
Email: altshulerh@gmail.com
Rússia, 18 Prosp. Sovetskii, Kemerovo, 650000; 6 Krasnaya St., Kemerovo, 650043
G. Al’tshuler
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
Email: altshulerh@gmail.com
Rússia, 18 Prosp. Sovetskii, Kemerovo, 650000
