Отправить статью по E-mail Immobilization of Benzocaine in Polymeric Nanocontainers. Pharmacokinetic Modeling
- Авторы: Shkurenko G.1, Lyrshchikov S.1, Gorlov A.1, Al’tshuler O.1,2, Al’tshuler G.1
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Учреждения:
- Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
- Kemerovo State University
- Выпуск: Том 52, № 5 (2018)
- Страницы: 464-466
- Раздел: Drug Synthesis Methods and Manufacturing Technology
- URL: https://journals.rcsi.science/0091-150X/article/view/245249
- DOI: https://doi.org/10.1007/s11094-018-1840-3
- ID: 245249
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Аннотация
The possibility of immobilizing benzocaine in polymeric nanocontainers made of sulfonated cation exchangers, i.e., sulfonated polycalixarene and KU-23 30/100, was studied. The desorption kinetics of neutral and cationic benzocaine from the polymeric nanocontainers provided the desired drug-release pharmacokinetics upon peroral administration.
Об авторах
G. Shkurenko
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
Email: altshulerh@gmail.com
Россия, 18 Prosp. Sovetskii, Kemerovo, 650000
S. Lyrshchikov
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
Email: altshulerh@gmail.com
Россия, 18 Prosp. Sovetskii, Kemerovo, 650000
A. Gorlov
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
Email: altshulerh@gmail.com
Россия, 18 Prosp. Sovetskii, Kemerovo, 650000
O. Al’tshuler
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences; Kemerovo State University
Автор, ответственный за переписку.
Email: altshulerh@gmail.com
Россия, 18 Prosp. Sovetskii, Kemerovo, 650000; 6 Krasnaya St., Kemerovo, 650043
G. Al’tshuler
Institute of Coal Chemistry and Materials Science, Federal Research Center of Coal and Coal Chemistry, Siberian Branch, Russian Academy of Sciences
Email: altshulerh@gmail.com
Россия, 18 Prosp. Sovetskii, Kemerovo, 650000
