Synthesis and Antimicrobial Properties of Ammonium Salts Containing a Substituted Butyn-2-yl Group

M. O. Manukyan; K. S. Barsegyan; A. Kh. Gyulnazaryan; R. V. Paronikyan; G. M. Stepanyan; N. S. Minasyan; A. V. Babakhanyan

doi:10.1007/s11094-017-1689-x

Synthesis and Antimicrobial Properties of Ammonium Salts Containing a Substituted Butyn-2-yl Group

Авторлар: Manukyan M.O.¹^,2, Barsegyan K.S.¹, Gyulnazaryan A.K.¹, Paronikyan R.V.³, Stepanyan G.M.³, Minasyan N.S.⁴, Babakhanyan A.V.²
Мекемелер:
1. Institute of Organic Chemistry, Scientific-Technical Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
2. Kh. Abovyan Armenian State Pedagogical University
3. A. L. Mndzhoyan Institute of Fine Organic Chemistry, Scientific-Technical Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
4. Center for Molecular Structure Studies, Scientific-Technical Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia
Шығарылым: Том 51, № 9 (2017)
Беттер: 764-768
Бөлім: Article
URL: https://journals.rcsi.science/0091-150X/article/view/244793
DOI: https://doi.org/10.1007/s11094-017-1689-x
ID: 244793

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Аннотация
Авторлар туралы
Әдебиет тізімі
Қосымша файлдар
Статистика

Аннотация

Interaction of 1-dimethylamino-4-diethylaminobutyn-2, 1-dimethylamino-4-piperidinobutyn-2, and 1-dimethylamino-4-morpholinobutyn-2 with the corresponding alkyl esters of monobromo(chloro)acetic acid was used to synthesize novel monoammonium salts. Studies of the antimicrobial activity of the resulting compounds showed that salts containing hydrophobic alkoxycarbonylmethyl radicals had marked antibacterial activity against Gram-positive and Gram-negative microorganisms.

Негізгі сөздер

diamines, ammonium salts, antimicrobial activity, Gram-positive and Gram-negative microorganisms

Авторлар туралы

M. Manukyan

Institute of Organic Chemistry, Scientific-Technical Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia; Kh. Abovyan Armenian State Pedagogical University

Хат алмасуға жауапты Автор.
Email: manukyanmeri@gmail.com
Армения, 26 Azatutyan Prospekt, Erevan, 0014; 17 Tigran Metsi Prospekt, Erevan, 0010

K. Barsegyan

Institute of Organic Chemistry, Scientific-Technical Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of the Republic of Armenia