Search for Bactericides Among Derivatives of Deoxyvasicinone, Mackinazolinone, and Thienopyrimidinones
- Авторлар: Ortikov I.1, Turdibaev Z.1, Islamova Z.1, Élmuradov B.1, Abdurazakov A.1, Bektemirov A.2, Osipova S.2, Khushbaktova Z.1, Syrov V.1, Shakhidoyatov K.1
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Мекемелер:
- S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
- Research Institute of Epidemiology, Microbiology, and Infectious Diseases, Ministry of Public Health of the Republic of Uzbekistan
- Шығарылым: Том 51, № 6 (2017)
- Беттер: 456-464
- Бөлім: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244652
- DOI: https://doi.org/10.1007/s11094-017-1633-0
- ID: 244652
Дәйексөз келтіру
Аннотация
Series of arylidene- and arylhydroxymethyl derivatives of 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-one and 2,3,4,10-tetrahydro-1H-pyrido[2,1-b]quinazolin-10-one were synthesized. Schiff bases were synthesized from amine derivatives. Hydroxymethylidene derivatives and arylaminomethylidene-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-9-ones and -2,3,4,10-tetrahydro-1H-pyrido[2,1-b]quinazolin-10-ones were obtained. The antimicrobial activity of the synthesized compounds against S. aureus, E. coli, Bacillus cereus, Candida albicans, and Pseudomonas aeruginosa was studied. It was concluded that the search for bactericides in these series was promising.
Авторлар туралы
I. Ortikov
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Өзбекстан, Tashkent
Zh. Turdibaev
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Өзбекстан, Tashkent
Zh. Islamova
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Өзбекстан, Tashkent
B. Élmuradov
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Өзбекстан, Tashkent
A. Abdurazakov
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Өзбекстан, Tashkent
A. Bektemirov
Research Institute of Epidemiology, Microbiology, and Infectious Diseases, Ministry of Public Health of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Өзбекстан, Tashkent
S. Osipova
Research Institute of Epidemiology, Microbiology, and Infectious Diseases, Ministry of Public Health of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Өзбекстан, Tashkent
Z. Khushbaktova
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Хат алмасуға жауапты Автор.
Email: zainab@icps.org.uz
Өзбекстан, Tashkent
V. Syrov
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Өзбекстан, Tashkent
Kh. Shakhidoyatov
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Өзбекстан, Tashkent