Search for Bactericides Among Derivatives of Deoxyvasicinone, Mackinazolinone, and Thienopyrimidinones
- Авторы: Ortikov I.1, Turdibaev Z.1, Islamova Z.1, Élmuradov B.1, Abdurazakov A.1, Bektemirov A.2, Osipova S.2, Khushbaktova Z.1, Syrov V.1, Shakhidoyatov K.1
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Учреждения:
- S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
- Research Institute of Epidemiology, Microbiology, and Infectious Diseases, Ministry of Public Health of the Republic of Uzbekistan
- Выпуск: Том 51, № 6 (2017)
- Страницы: 456-464
- Раздел: Article
- URL: https://journals.rcsi.science/0091-150X/article/view/244652
- DOI: https://doi.org/10.1007/s11094-017-1633-0
- ID: 244652
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Аннотация
Series of arylidene- and arylhydroxymethyl derivatives of 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-3-one and 2,3,4,10-tetrahydro-1H-pyrido[2,1-b]quinazolin-10-one were synthesized. Schiff bases were synthesized from amine derivatives. Hydroxymethylidene derivatives and arylaminomethylidene-1,2,3,9-tetrahydropyrrolo[2,1-b]quinazolin-9-ones and -2,3,4,10-tetrahydro-1H-pyrido[2,1-b]quinazolin-10-ones were obtained. The antimicrobial activity of the synthesized compounds against S. aureus, E. coli, Bacillus cereus, Candida albicans, and Pseudomonas aeruginosa was studied. It was concluded that the search for bactericides in these series was promising.
Об авторах
I. Ortikov
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Узбекистан, Tashkent
Zh. Turdibaev
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Узбекистан, Tashkent
Zh. Islamova
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Узбекистан, Tashkent
B. Élmuradov
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Узбекистан, Tashkent
A. Abdurazakov
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Узбекистан, Tashkent
A. Bektemirov
Research Institute of Epidemiology, Microbiology, and Infectious Diseases, Ministry of Public Health of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Узбекистан, Tashkent
S. Osipova
Research Institute of Epidemiology, Microbiology, and Infectious Diseases, Ministry of Public Health of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Узбекистан, Tashkent
Z. Khushbaktova
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Автор, ответственный за переписку.
Email: zainab@icps.org.uz
Узбекистан, Tashkent
V. Syrov
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Узбекистан, Tashkent
Kh. Shakhidoyatov
S. Yu. Yunusov Institute of the Chemistry of Plant Substances, Academy of Sciences of the Republic of Uzbekistan
Email: zainab@icps.org.uz
Узбекистан, Tashkent