Uspehi sovremennoj biologii

The journal is a source of up-to-date and comprehensive information on the state and achievements of current biology, and covers a variety of biological disciplines including

biogeography, botany, zoology, paleontology, embryology, taxonomy, evolutionary theory, physiology, and ecology. The journal also considers all aspects of adaptive mechanisms

and strategies, problems of genetics and molecular biology, current taxonomy, ethology, and biomedical problems. The focus of the journal is general biological problems related

to the organization and development of different life forms on the Earth. Although the journal is broad-scoped, it encourages publications dealing with biological macroobjects

(organisms, populations, and communities), since these studies form the basis of general biological theories and concepts.

Current Issue

Open Access Open Access  Restricted Access Access granted  Restricted Access Subscription Access

Vol 143, No 3 (2023)

Cover Page

Full Issue

Open Access Open Access
Restricted Access Access granted
Restricted Access Subscription Access


Dynamics of Commensals Virulence: Preventive Phenotypical Mutability
Chepur S.V., Pluzhnikov N.N., Saiganov S.A., Chubar O.V., Bakulina L.S., Litvinenko I.V.

The peculiarities of the influence of cytokines and metabolites of the systemic inflammatory reaction, stress-implementing and nutritional factors contributing to the transformation of the phenotype of the resident intestinal microflora with an increase in its virulence are described. From the perspective of gene expression, protein and phospholipids conformations, the influence of temperature as a signaling factor in increasing the virulence of the intestinal microbiome is considered. Evolutionarily formed mechanisms of expression of the maximum pathogenic phenotype of microorganisms and, thus, achieving an increase in their biomass and maximum dissemination through the microorganism compartments increases the probability of the commensals transmission to another biotope, i.e. increases the probability of their survival after the death of the host organism. To prevent bacterial translocation after the relief of critical conditions, early enteral administration of β-glucans in food mixtures, iron excretion, relief of inorganic phosphate deficiency, including by induction of alkaline phosphatase synthesis.

Uspehi sovremennoj biologii. 2023;143(3):197-217
pages 197-217 views
Diagnostic and Therapeutic Approach to Multisystem Inflammatory Syndrome and Similar Condition
Emami A., Yeganeh S.A., Mohammadi H.A., Shahbazi T.

Multisystem inflammatory syndrome (MIS-C) can occur in kids, who have severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). Clinically, characteristics of MIS-C are manifested by two or more involved organ systems, fever, severe illness, laboratory-evidenced inflammation, and laboratory or epidemiologically e-videnced infection with SARS-CoV-2. MIS-C has several traits with Kawasaki illness, subsequent hemophagocytic lymphohistiocytosis/macrophage activation syndrome, and toxic shock syndrome. The association between MIS-C and infection with SARS-CoV-2 shows the cause of post-infectious immunological dysregulation. Given the likelihood of rapid clinical deterioration, it is recommended to handle MIS-C patients in a pediatric critical care unit. Depending on the clinical presentation, a certain immunomodulatory therapy is advised. More research is needed to determine the connection between MIS-C and the immunological reaction to SARS-CoV-2 vaccines that are currently being developed. Numerous therapeutic methods have been developed for the treatment of COVID-19-associated MIS in children (MIS-C), the full elucidation of its etiology requires further studies. Here, we carefully review and summarize the previously released management guidance.

Uspehi sovremennoj biologii. 2023;143(3):218-228
pages 218-228 views
Post-Covid Syndrome: Pathophysiology of Systemic Disregulations
Gomazkov O.A.

The main processes that characterize the post-COVID syndrome are analyzed as a version of the “prolonged” pathology of acute COVID-19. Considering the variety of manifestations of post-covid pathology, the main blocks of systemic, cellular and molecular dysregulations are distinguished. As the main reasons, the following are considered: the consequences of systemic and organ damage in the acute phase of COVID-19, the persistent activity of “hidden” pathogens and the altered status of the patient’s protective immune systems. Long-term pathology, as a multisystem syndrome, reflects disturbances in the main cellular and molecular regulatory systems: stochastic disorganization of immune responses, vascular endothelial dysfunction, cellular inflammation, imbalance of coagulation and antithrombosis systems, deviations in autoimmune processes, etc. These findings orient new cellular and biochemical targets for timely therapy. The varied nature of the symptoms suggests a selective use of therapeutic approaches.

Uspehi sovremennoj biologii. 2023;143(3):229-238
pages 229-238 views
Bacteriophages and their Endolysin: An Alternative Therapeutic Approach for Bovine Mastitis
Kanwar R., Aslam M.A., Zulqurnain H., Qadeer A., Ali S., Nayab S., Mustafa S.

Mastitis is one of the most prevalent and serious disease in bovines and led to high economic loss in the dairy industry. Mastitis dramatically reduces the reproduction abilities of cows. Despite significant progress in controlling and treating this disease, it is still frequent. Mastitis risks public health if milk from treated animals is taken by humans. Multiple factors are responsible for this disease, but bacterial mastitis is the most prevalent and threatening. The emergence of drug-resistant bacterial strains makes mastitis untreatable. Misuse of antibiotics in animal therapy is responsible for this issue, which resulted in the creation of strains that are multidrug resistant. This antibiotic resistance among bacteria is alarming. There is a need for an alternative treatment to cure mastitis. Bacteriophages are viruses, which kill bacteria. The effectiveness of bacteriophages and their endolysin against different bacterial infections causing mastitis has been approved from the results of various studies. Phage therapy is used as both a treatment and preventive measure.

Uspehi sovremennoj biologii. 2023;143(3):239-249
pages 239-249 views
Abundance and Condition of Populations of Small Mammals as Carriers of Natural Focal Human Diseases in the Karelia North-East Ladoga
Ivanter E.V.

Summing up the results of the long-term studies of population ecology and dynamics of small mammals for more than half a century (1966–2018). Small mammals are involved in the formation and functioning of natural-focil of human vector-borne diseases common in the North-Eastern Ladoga region. Encephalitis and tularemia circulate intensively in the Ladoga region under conditions of intensive anthropogenic transformation of taiga ecosystems. Local landscapes belong to the subzone of the middle taiga forests. Most of the studied species of small mammals are located in the northern periphery of this area. Here representatives of the native taiga fauna of Micromammalia constantly experience powerful anthropogenic pressure, which leads to a decrease in their abundance and correlation of the species. Of the total amount of 22 species of small mammals collected here, Sorex araneus and Myodes glareolus dominate. Next, the species prevalent (according to the degree of predominant species) in the counts are Microtus agrestis, Sorex minutus and Sorex caecutiens. Other species are relatively rare and appear in smaller numbers. Myodes glareolus has main role in the feeding of ticks and, accordingly, in the circulation of infections in nature, the differentiated contribution of individual intrapopulation groups in maintaining the number of vectors and the activity of pathogens. Shrews are important for the development of the larval stages of the tick. In the research area, were recorded total index of trap catch of abundance of small animals with trap lines from 0.34 to 18.5 individuals per 100 snap traps-nights (average of 7.8 ind.) and with pitfall traps recorded from 2.7 to 25.4 individuals per 10 ditch-nights (average of 14 ind.). This indicates that the studied area has smaller amount of mammals compared to other regions in Southern Europe. Nevertheless, the studies determine a rather tense epidemic situation in the studied area. Population of small mammals of boreal ecosystem steadily affect the mass feeding of carriers of natural focal infections.

Uspehi sovremennoj biologii. 2023;143(3):250-260
pages 250-260 views
Genetic Diversity of the European Perch ( Linnaeus, 1758) from Some Rivers of Russia
Bachevskaya L.T., Pereverzeva V.V., Agapova G.A., Primak A.A.

Data on the nucleotide sequence variability of the mtDNA cytochrome b gene of the European perch (Perca fluviatilis Linnaeus, 1758) from the rivers of the Volga and the Kolyma basins were obtained. An assessment of the genetic diversity of the European perch from the studied populations was carried out. A high level of divergence was noted between the perch samples from the rivers of different regions. At the same time, it was shown that, according to the genetic parameters, the samples of the European perch from the rivers of the same water basin had statistically significant differences. Phylogenetic analysis based on the found haplotypes of the mtDNA cytochrome b gene led to the conclusion that the Kolyma perch cannot claim the status of a subspecies of P. fluviatilis.

Uspehi sovremennoj biologii. 2023;143(3):261-269
pages 261-269 views
The Effect of Gonads Maturation on Lysozyme of Pike Females (Esocidae)
Subbotkin M.F., Subbotkina T.A.

The effect of the gonad development in the pike Esox lucius females on the quantitative parameters of the lysozyme, a component of nonspecific resistance, and the size of some the immune system organs was studied from September to April. The variability of the lysozyme concentration as an indicator of the amount of enzyme in a fixed dimension, as well as the total amount of lysozyme in the whole organ was evaluated. It is established that during the period of female maturation and gonad development the concentration of lysozyme in the serum and spleen significantly decreases. At this time, the size of the liver increases, and the spleen decreases, the kidney index remains unchanged. The concentration of lysozyme in the liver and serum is inversely correlated with the increase of the gonads, but the dependence on the gonads size is weak. The growth of the gonads and a significant increase in the size of the liver do not affect the lysozyme index of the liver, which reflects the total amount of the enzyme in this organ. It was found that the decrease in the enzyme concentration in the liver is proportional to the increase in the size of the organ. A direct relationship was found between the quantitative parameters of the lysozyme in the kidney and the total amount of the enzyme and the size of the spleen, therefore, a decrease in the concentration and total amount of lysozyme in the kidney may be a manifestation of the indirect effect of gonad maturation. The concentration of lysozyme in the serum showed a direct relationship with the water temperature of the water body, but such a relationship was not manifested in the organs. In the studied period, the quantitative parameters of the enzyme in the spleen and the relative size of the organ turned out to be more related to the water temperature than to the gonadosomatic index. The maturation of the gonads in females, combined with the external influence of temperature, has both a direct and indirect effect on the concentration of lysozyme in tissues. The concentration of tissue lysozyme as an indicator with a fixed dimension can be determined not only by the state of immunity, but also by changes in the size of organs. Determination of the total amount of lysozyme in the immune system organs increases the objectivity of assessing the influence of the physiological state of the organism on the nonspecific immunity of fish.

Uspehi sovremennoj biologii. 2023;143(3):270-277
pages 270-277 views
Nanomaterials in Plant Protection against Parasitic Nemates
Zinovieva S.V., Udalova Z.V., Khasanovа O.S.

A review of current data on the effect of nanoparticles on phytoparasitic nematodes in the study in vitro and in planta and on plants infested with nematodes was carried out. Available data have shown that many nanoparticles of metals, metal oxides and non-metals have an effective nematicidal potential. According to the available data, NPs can have a direct toxic effect on nematodes, reduce the infection of plants during seed pretreatment or spraying, lead to inhibition of reproduction and development of the parasite in the roots, and their effectiveness may exceed known commercial nematicides. Some nanoparticles have an immunostimulatory effect on plants. Data on the mechanisms of action of NPs on nematodes are presented. An important mechanism for the toxicity of nanoparticles to nematodes may be the generation of reactive oxygen species (oxidative stress). Exposure to nanoparticles increased the expression of target genes involved in oxidative stress and DNA damage repair. A small number of works have dealt with nanonematicides, which in the form of nanocapsules have proven to be very effective against endoparasitic nematodes.

Uspehi sovremennoj biologii. 2023;143(3):278-299
pages 278-299 views
Environmental Digitalization as a Task of Engineering Environment (Review of the Problem)
Rozenberg G.S., Kostina N.V., Kudinova G.E., Rozenberg A.G.

Digitalization (development of the information society) affects all aspects of our life, having an increasingly noticeable (both positive and negative) impact on the environment. Some information technologies in the field of ecology, directions, goals and objectives of digitalization of environmental knowledge and nature management in Russia are discussed.

Uspehi sovremennoj biologii. 2023;143(3):300-312
pages 300-312 views

This website uses cookies

You consent to our cookies if you continue to use our website.

About Cookies