Antibacterial Activity of Hybrid Polymeric Scaffold for Reconstruction of Tubular Bone Defects
- 作者: Anisimova N.1,2, Zalepugin D.2, Chernyshova I.2, Maksimkin A.2, Kiselevskii M.1, Senatov F.2, Spirina T.1, Sitdikova S.1, Karaulov A.3
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隶属关系:
- Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
- Center for Composite Materials, National University of Science and Technology MISIS
- Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University (Sechenov University)
- 期: 卷 168, 编号 1 (2019)
- 页面: 58-61
- 栏目: Immunology and Microbiology
- URL: https://journals.rcsi.science/0007-4888/article/view/242206
- DOI: https://doi.org/10.1007/s10517-019-04646-2
- ID: 242206
如何引用文章
详细
We studied antibacterial activity of a hybrid polymeric construction consisting of continuous and porous layers of ultrahigh-molecular-weight polyethylene reinforced by titanium. Experimental samples were impregnated with amoxycillin in subcritical Freon R22. The contact of bacterial culture with hybrid polymeric constructions saturated with amoxycillin suppressed the growth of microorganisms and the formation of their colonies. These results attest to the presence of a bactericidal effect of hybrid scaffold samples impregnated with an antibacterial component.
作者简介
N. Anisimova
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation; Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
俄罗斯联邦, Moscow; Moscow
D. Zalepugin
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
俄罗斯联邦, Moscow
I. Chernyshova
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
俄罗斯联邦, Moscow
A. Maksimkin
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
俄罗斯联邦, Moscow
M. Kiselevskii
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
编辑信件的主要联系方式.
Email: kisele@inbox.ru
俄罗斯联邦, Moscow
F. Senatov
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
俄罗斯联邦, Moscow
T. Spirina
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Email: kisele@inbox.ru
俄罗斯联邦, Moscow
S. Sitdikova
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Email: kisele@inbox.ru
俄罗斯联邦, Moscow
A. Karaulov
Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University (Sechenov University)
Email: kisele@inbox.ru
俄罗斯联邦, Moscow