Antibacterial Activity of Hybrid Polymeric Scaffold for Reconstruction of Tubular Bone Defects


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We studied antibacterial activity of a hybrid polymeric construction consisting of continuous and porous layers of ultrahigh-molecular-weight polyethylene reinforced by titanium. Experimental samples were impregnated with amoxycillin in subcritical Freon R22. The contact of bacterial culture with hybrid polymeric constructions saturated with amoxycillin suppressed the growth of microorganisms and the formation of their colonies. These results attest to the presence of a bactericidal effect of hybrid scaffold samples impregnated with an antibacterial component.

作者简介

N. Anisimova

Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation; Center for Composite Materials, National University of Science and Technology MISIS

Email: kisele@inbox.ru
俄罗斯联邦, Moscow; Moscow

D. Zalepugin

Center for Composite Materials, National University of Science and Technology MISIS

Email: kisele@inbox.ru
俄罗斯联邦, Moscow

I. Chernyshova

Center for Composite Materials, National University of Science and Technology MISIS

Email: kisele@inbox.ru
俄罗斯联邦, Moscow

A. Maksimkin

Center for Composite Materials, National University of Science and Technology MISIS

Email: kisele@inbox.ru
俄罗斯联邦, Moscow

M. Kiselevskii

Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation

编辑信件的主要联系方式.
Email: kisele@inbox.ru
俄罗斯联邦, Moscow

F. Senatov

Center for Composite Materials, National University of Science and Technology MISIS

Email: kisele@inbox.ru
俄罗斯联邦, Moscow

T. Spirina

Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation

Email: kisele@inbox.ru
俄罗斯联邦, Moscow

S. Sitdikova

Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation

Email: kisele@inbox.ru
俄罗斯联邦, Moscow

A. Karaulov

Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University (Sechenov University)

Email: kisele@inbox.ru
俄罗斯联邦, Moscow


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