Antibacterial Activity of Hybrid Polymeric Scaffold for Reconstruction of Tubular Bone Defects
- Авторлар: Anisimova N.1,2, Zalepugin D.2, Chernyshova I.2, Maksimkin A.2, Kiselevskii M.1, Senatov F.2, Spirina T.1, Sitdikova S.1, Karaulov A.3
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Мекемелер:
- Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
- Center for Composite Materials, National University of Science and Technology MISIS
- Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University (Sechenov University)
- Шығарылым: Том 168, № 1 (2019)
- Беттер: 58-61
- Бөлім: Immunology and Microbiology
- URL: https://journals.rcsi.science/0007-4888/article/view/242206
- DOI: https://doi.org/10.1007/s10517-019-04646-2
- ID: 242206
Дәйексөз келтіру
Аннотация
We studied antibacterial activity of a hybrid polymeric construction consisting of continuous and porous layers of ultrahigh-molecular-weight polyethylene reinforced by titanium. Experimental samples were impregnated with amoxycillin in subcritical Freon R22. The contact of bacterial culture with hybrid polymeric constructions saturated with amoxycillin suppressed the growth of microorganisms and the formation of their colonies. These results attest to the presence of a bactericidal effect of hybrid scaffold samples impregnated with an antibacterial component.
Авторлар туралы
N. Anisimova
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation; Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
Ресей, Moscow; Moscow
D. Zalepugin
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
Ресей, Moscow
I. Chernyshova
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
Ресей, Moscow
A. Maksimkin
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
Ресей, Moscow
M. Kiselevskii
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Хат алмасуға жауапты Автор.
Email: kisele@inbox.ru
Ресей, Moscow
F. Senatov
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
Ресей, Moscow
T. Spirina
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Email: kisele@inbox.ru
Ресей, Moscow
S. Sitdikova
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Email: kisele@inbox.ru
Ресей, Moscow
A. Karaulov
Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University (Sechenov University)
Email: kisele@inbox.ru
Ресей, Moscow