Enviar artigo por via de e-mail Antibacterial Activity of Hybrid Polymeric Scaffold for Reconstruction of Tubular Bone Defects
- Autores: Anisimova N.1,2, Zalepugin D.2, Chernyshova I.2, Maksimkin A.2, Kiselevskii M.1, Senatov F.2, Spirina T.1, Sitdikova S.1, Karaulov A.3
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Afiliações:
- Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
- Center for Composite Materials, National University of Science and Technology MISIS
- Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University (Sechenov University)
- Edição: Volume 168, Nº 1 (2019)
- Páginas: 58-61
- Seção: Immunology and Microbiology
- URL: https://journals.rcsi.science/0007-4888/article/view/242206
- DOI: https://doi.org/10.1007/s10517-019-04646-2
- ID: 242206
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Resumo
We studied antibacterial activity of a hybrid polymeric construction consisting of continuous and porous layers of ultrahigh-molecular-weight polyethylene reinforced by titanium. Experimental samples were impregnated with amoxycillin in subcritical Freon R22. The contact of bacterial culture with hybrid polymeric constructions saturated with amoxycillin suppressed the growth of microorganisms and the formation of their colonies. These results attest to the presence of a bactericidal effect of hybrid scaffold samples impregnated with an antibacterial component.
Sobre autores
N. Anisimova
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation; Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
Rússia, Moscow; Moscow
D. Zalepugin
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
Rússia, Moscow
I. Chernyshova
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
Rússia, Moscow
A. Maksimkin
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
Rússia, Moscow
M. Kiselevskii
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: kisele@inbox.ru
Rússia, Moscow
F. Senatov
Center for Composite Materials, National University of Science and Technology MISIS
Email: kisele@inbox.ru
Rússia, Moscow
T. Spirina
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Email: kisele@inbox.ru
Rússia, Moscow
S. Sitdikova
Laboratory of Cellular Immunity, N. N. Blokhin National Medical Research Center of Oncology, Ministry of Health of the Russian Federation
Email: kisele@inbox.ru
Rússia, Moscow
A. Karaulov
Department of Clinical Immunology and Allergology, I. M. Sechenov First Moscow State Medical University (Sechenov University)
Email: kisele@inbox.ru
Rússia, Moscow
