Effect of Stimulation of α2-Adrenergic Receptors on Action Potential of Working Cardiomyocytes in Rat Atrium
- 作者: Zefirov T.1, Faskhutdinov L.1, Ziyatdinova N.1, Galieva A.1, Zefirov A.2
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隶属关系:
- Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
- Department of Normal Physiology, Kazan State Medical University
- 期: 卷 167, 编号 5 (2019)
- 页面: 603-605
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241954
- DOI: https://doi.org/10.1007/s10517-019-04579-w
- ID: 241954
如何引用文章
详细
The study examined the effect of clonidine hydrochloride (10—9-10—5 М) on electrical activity of working cardiomyocytes in rat right atrium. Stimulation of α2-adrenergic receptor with clonidine changed electrical activity of the heart. All tested concentrations of the agonist lengthened the action potential and decreased the firing rate of cardiomyocytes in a dose-dependent manner. The maximum effects of clonidine were observed at concentration of 10—5 М.
作者简介
T. Zefirov
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
编辑信件的主要联系方式.
Email: zefirovtl@mail.ru
俄罗斯联邦, Kazan
L. Faskhutdinov
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
俄罗斯联邦, Kazan
N. Ziyatdinova
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
俄罗斯联邦, Kazan
A. Galieva
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
俄罗斯联邦, Kazan
A. Zefirov
Department of Normal Physiology, Kazan State Medical University
Email: zefirovtl@mail.ru
俄罗斯联邦, Kazan, Republic of Tatarstan