Enviar artigo por via de e-mail Effect of Stimulation of α2-Adrenergic Receptors on Action Potential of Working Cardiomyocytes in Rat Atrium
- Autores: Zefirov T.1, Faskhutdinov L.1, Ziyatdinova N.1, Galieva A.1, Zefirov A.2
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Afiliações:
- Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
- Department of Normal Physiology, Kazan State Medical University
- Edição: Volume 167, Nº 5 (2019)
- Páginas: 603-605
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241954
- DOI: https://doi.org/10.1007/s10517-019-04579-w
- ID: 241954
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Resumo
The study examined the effect of clonidine hydrochloride (10—9-10—5 М) on electrical activity of working cardiomyocytes in rat right atrium. Stimulation of α2-adrenergic receptor with clonidine changed electrical activity of the heart. All tested concentrations of the agonist lengthened the action potential and decreased the firing rate of cardiomyocytes in a dose-dependent manner. The maximum effects of clonidine were observed at concentration of 10—5 М.
Sobre autores
T. Zefirov
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Autor responsável pela correspondência
Email: zefirovtl@mail.ru
Rússia, Kazan
L. Faskhutdinov
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
Rússia, Kazan
N. Ziyatdinova
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
Rússia, Kazan
A. Galieva
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
Rússia, Kazan
A. Zefirov
Department of Normal Physiology, Kazan State Medical University
Email: zefirovtl@mail.ru
Rússia, Kazan, Republic of Tatarstan
