Effect of Stimulation of α2-Adrenergic Receptors on Action Potential of Working Cardiomyocytes in Rat Atrium
- Авторы: Zefirov T.L.1, Faskhutdinov L.I.1, Ziyatdinova N.I.1, Galieva A.M.1, Zefirov A.L.2
- 
							Учреждения: 
							- Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
- Department of Normal Physiology, Kazan State Medical University
 
- Выпуск: Том 167, № 5 (2019)
- Страницы: 603-605
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241954
- DOI: https://doi.org/10.1007/s10517-019-04579-w
- ID: 241954
Цитировать
Аннотация
The study examined the effect of clonidine hydrochloride (10—9-10—5 М) on electrical activity of working cardiomyocytes in rat right atrium. Stimulation of α2-adrenergic receptor with clonidine changed electrical activity of the heart. All tested concentrations of the agonist lengthened the action potential and decreased the firing rate of cardiomyocytes in a dose-dependent manner. The maximum effects of clonidine were observed at concentration of 10—5 М.
Об авторах
T. Zefirov
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
							Автор, ответственный за переписку.
							Email: zefirovtl@mail.ru
				                					                																			                												                	Россия, 							Kazan						
L. Faskhutdinov
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
														Email: zefirovtl@mail.ru
				                					                																			                												                	Россия, 							Kazan						
N. Ziyatdinova
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
														Email: zefirovtl@mail.ru
				                					                																			                												                	Россия, 							Kazan						
A. Galieva
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
														Email: zefirovtl@mail.ru
				                					                																			                												                	Россия, 							Kazan						
A. Zefirov
Department of Normal Physiology, Kazan State Medical University
														Email: zefirovtl@mail.ru
				                					                																			                												                	Россия, 							Kazan, Republic of Tatarstan						
Дополнительные файлы
 
				
			 
						 
					 
						 
						 
						 
									 
  
  
  
  
  Отправить статью по E-mail
			Отправить статью по E-mail  Открытый доступ
		                                Открытый доступ Доступ предоставлен
						Доступ предоставлен Только для подписчиков
		                                		                                        Только для подписчиков
		                                					