Cell Death and Development of Fibrotic Alterations in Lung Granuloma of BALB/c Mice during Chronic BCG-Induced Granulomatosis
- 作者: Cherdantseva L.1, Potapova O.2, Sharkova T.2, Anikina A.1, Kovner A.1, Troitskii A.1, Shkurupy V.3
-
隶属关系:
- Research Institute of Experimental and Clinical Medicine
- Optimum Medical Laboratory, Research-and-Educational Center
- Novosibirsk State Medical University, Ministry of Health of the Russian Federation
- 期: 卷 165, 编号 1 (2018)
- 页面: 48-51
- 栏目: Microbiology and Immunology
- URL: https://journals.rcsi.science/0007-4888/article/view/239967
- DOI: https://doi.org/10.1007/s10517-018-4096-8
- ID: 239967
如何引用文章
详细
Light microscopy, immunohistochemistry, and morphometric examinations established that cell death in lung granulomas of BCG-infected mice resulted mainly from activation of receptor-mediated apoptosis, which did not prevent the persistence of the causative agent in macrophages of the granulomas and promoted the formation of pronounced fibrosis in granulomas and pulmonary interstitium.
作者简介
L. Cherdantseva
Research Institute of Experimental and Clinical Medicine
编辑信件的主要联系方式.
Email: cherdanceff@yandex.ru
俄罗斯联邦, Novosibirsk
O. Potapova
Optimum Medical Laboratory, Research-and-Educational Center
Email: cherdanceff@yandex.ru
俄罗斯联邦, Sochi
T. Sharkova
Optimum Medical Laboratory, Research-and-Educational Center
Email: cherdanceff@yandex.ru
俄罗斯联邦, Sochi
A. Anikina
Research Institute of Experimental and Clinical Medicine
Email: cherdanceff@yandex.ru
俄罗斯联邦, Novosibirsk
A. Kovner
Research Institute of Experimental and Clinical Medicine
Email: cherdanceff@yandex.ru
俄罗斯联邦, Novosibirsk
A. Troitskii
Research Institute of Experimental and Clinical Medicine
Email: cherdanceff@yandex.ru
俄罗斯联邦, Novosibirsk
V. Shkurupy
Novosibirsk State Medical University, Ministry of Health of the Russian Federation
Email: cherdanceff@yandex.ru
俄罗斯联邦, Novosibirsk
![](/img/style/loading.gif)