Ultrastructure of Rat Kidneys after Intravenous Administration of Modified Magnetite Nanoparticles
- 作者: Mil’to I.1,2, Sukhodolo I.1, Ivanova V.1, Yusubov M.1,3
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隶属关系:
- Department of Morphology and General Pathology, Siberian State Medical University, Ministry of the Health of the Russian Federation
- Department of Biotechnology and Organic Chemistry
- Department of Technology of Organic Substances and Polymeric Materials, National Research Tomsk Polytechnic University
- 期: 卷 164, 编号 2 (2017)
- 页面: 218-222
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/239515
- DOI: https://doi.org/10.1007/s10517-017-3962-0
- ID: 239515
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详细
The ultrastructure of nephrocytes of the proximal and distal convoluted tubules, podocytes, mesangial cells, and macrophages of the interstitial connective tissue was studied after single intravenous administration of magnetite nanoparticles modified with chitosan (magnetic nanospheres) or lipids (magnetic liposomes). Transmission electron microscopy showed ultrastructural features of absorption of magnetite nanoparticles. The shape, size, and number of vesicles containing nanoparticles in nephrocytes of convoluted tubules and macrophages after administration of the suspensions of magnetic nanospheres and magnetic liposomes were described.
作者简介
I. Mil’to
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of the Health of the Russian Federation; Department of Biotechnology and Organic Chemistry
编辑信件的主要联系方式.
Email: milto_bio@mail.ru
俄罗斯联邦, Tomsk; Tomsk
I. Sukhodolo
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of the Health of the Russian Federation
Email: milto_bio@mail.ru
俄罗斯联邦, Tomsk
V. Ivanova
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of the Health of the Russian Federation
Email: milto_bio@mail.ru
俄罗斯联邦, Tomsk
M. Yusubov
Department of Morphology and General Pathology, Siberian State Medical University, Ministry of the Health of the Russian Federation; Department of Technology of Organic Substances and Polymeric Materials, National Research Tomsk Polytechnic University
Email: milto_bio@mail.ru
俄罗斯联邦, Tomsk; Tomsk