电邮这篇文章 Effect of Selank on Spontaneous Synaptic Activity of Rat Hippocampal CA1 Neurons
- 作者: Povarov I.1, Kondratenko R.1, Derevyagin V.1, Myasoedov N.2, Skrebitsky V.1
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隶属关系:
- Research Center of Neurology
- Institute of Molecular Genetics, Russian Academy of Sciences
- 期: 卷 162, 编号 5 (2017)
- 页面: 640-642
- 栏目: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/238425
- DOI: https://doi.org/10.1007/s10517-017-3676-3
- ID: 238425
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详细
Application of anxiolytic drug Selank to hippocampal slices increased the amplitude and discharge rate of spontaneous inhibitory postsynaptic currents in rat hippocampal pyramidal CA1 neurons. In some neurons, Selank-induced up-regulation of spontaneous inhibitory postsynaptic currents was preceded by a transient decrease in this activity. In the examined concentration range (1-8 μM), Selank demonstrated no significant dose-dependence.
作者简介
I. Povarov
Research Center of Neurology
编辑信件的主要联系方式.
Email: povarovigor@mail.ru
俄罗斯联邦, Moscow
R. Kondratenko
Research Center of Neurology
Email: povarovigor@mail.ru
俄罗斯联邦, Moscow
V. Derevyagin
Research Center of Neurology
Email: povarovigor@mail.ru
俄罗斯联邦, Moscow
N. Myasoedov
Institute of Molecular Genetics, Russian Academy of Sciences
Email: povarovigor@mail.ru
俄罗斯联邦, Moscow
V. Skrebitsky
Research Center of Neurology
Email: povarovigor@mail.ru
俄罗斯联邦, Moscow
