Antiproliferative Effects of Mesenchymal Stem Cells and Epithelial Cells on Lymphocytes
- 作者: Svirshchevskaya E.1, Poltavtseva R.2, Beletskii I.2, Selezneva I.3, Sukhikh G.1
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隶属关系:
- M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
- Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
- 期: 卷 161, 编号 4 (2016)
- 页面: 518-522
- 栏目: Microbiology and Immunology
- URL: https://journals.rcsi.science/0007-4888/article/view/237559
- DOI: https://doi.org/10.1007/s10517-016-3451-x
- ID: 237559
如何引用文章
详细
We analyzed the interactions between peripheral blood lymphocytes from heterologous donors with mesenchymal stem cells obtained from the tooth pulp and trophoblast. In mixed cultures, proliferation of both lymphocytes and mesenchymal stem cells was suppressed. Similar suppressive effects were observed in lymphocyte cultures mixed with epithelial cells (hepatocytes HeG2 and renal epithelial cells HEK293). This suppression can be determined by impairment of normal adhesion contacts between cells of different origin.
作者简介
E. Svirshchevskaya
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
编辑信件的主要联系方式.
Email: esvir@mx.ibch.ru
俄罗斯联邦, Moscow
R. Poltavtseva
V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: esvir@mx.ibch.ru
俄罗斯联邦, Moscow
I. Beletskii
V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: esvir@mx.ibch.ru
俄罗斯联邦, Moscow
I. Selezneva
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: esvir@mx.ibch.ru
俄罗斯联邦, Pushchino, Moscow region
G. Sukhikh
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: esvir@mx.ibch.ru
俄罗斯联邦, Moscow
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