Antiproliferative Effects of Mesenchymal Stem Cells and Epithelial Cells on Lymphocytes
- Авторлар: Svirshchevskaya E.1, Poltavtseva R.2, Beletskii I.2, Selezneva I.3, Sukhikh G.1
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Мекемелер:
- M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
- V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
- Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
- Шығарылым: Том 161, № 4 (2016)
- Беттер: 518-522
- Бөлім: Microbiology and Immunology
- URL: https://journals.rcsi.science/0007-4888/article/view/237559
- DOI: https://doi.org/10.1007/s10517-016-3451-x
- ID: 237559
Дәйексөз келтіру
Аннотация
We analyzed the interactions between peripheral blood lymphocytes from heterologous donors with mesenchymal stem cells obtained from the tooth pulp and trophoblast. In mixed cultures, proliferation of both lymphocytes and mesenchymal stem cells was suppressed. Similar suppressive effects were observed in lymphocyte cultures mixed with epithelial cells (hepatocytes HeG2 and renal epithelial cells HEK293). This suppression can be determined by impairment of normal adhesion contacts between cells of different origin.
Авторлар туралы
E. Svirshchevskaya
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Хат алмасуға жауапты Автор.
Email: esvir@mx.ibch.ru
Ресей, Moscow
R. Poltavtseva
V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: esvir@mx.ibch.ru
Ресей, Moscow
I. Beletskii
V. I. Kulakov Research Center for Obstetrics, Gynecology, and Perinatology, Ministry of Health of the Russian Federation
Email: esvir@mx.ibch.ru
Ресей, Moscow
I. Selezneva
Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences
Email: esvir@mx.ibch.ru
Ресей, Pushchino, Moscow region
G. Sukhikh
M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences
Email: esvir@mx.ibch.ru
Ресей, Moscow
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