Population Polymorphism of IFNL3 and IFNL4 Genes of Type 3 Interferon Associated with Spontaneous Clearance of Hepatitis C Virus in Representatives of Caucasian and Mongoloid Races
- 作者: Malov I.1, Malov S.1, Savilov E.2,3, Gantulga D.4, Stepanenko L.1, Ogarkov O.2,3, Nyamkhuu D.4, Aitov K.1, Nyamdawa P.4, Kolesnikov S.2
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隶属关系:
- Irkutsk State Medical University
- Research Center of Problems of Family Health and Human Reproduction
- Irkutsk State Medical Academy of Post-Graduate Education
- National Center of Investigation of Infectious Diseases
- 期: 卷 161, 编号 3 (2016)
- 页面: 404-407
- 栏目: Virology
- URL: https://journals.rcsi.science/0007-4888/article/view/237463
- DOI: https://doi.org/10.1007/s10517-016-3425-z
- ID: 237463
如何引用文章
详细
The frequency of single nucleotide polymorphisms of IFNL3 gene (rsl12979860 and rs8099917) and dinucleotide polymorphism of IFNL4 gene (ss469415590) were estimated in healthy inhabitants of Mongolia and Irkutsk regions taking into account their races. Population and genetic studies were performed in 1520 conventionally healthy volunteers (blood donors), representatives of Caucasian and Mongoloid races. Significant race-related differences in the incidence of IFNL3 and IFNL4 gene polymorphisms associated with spontaneous clearance of hepatitis C virus were found in healthy volunteers.
作者简介
I. Malov
Irkutsk State Medical University
Email: sikolesnikov2012@gmail.com
俄罗斯联邦, Irkutsk
S. Malov
Irkutsk State Medical University
编辑信件的主要联系方式.
Email: sikolesnikov2012@gmail.com
俄罗斯联邦, Irkutsk
E. Savilov
Research Center of Problems of Family Health and Human Reproduction; Irkutsk State Medical Academy of Post-Graduate Education
Email: sikolesnikov2012@gmail.com
俄罗斯联邦, Irkutsk; Irkutsk
D. Gantulga
National Center of Investigation of Infectious Diseases
Email: sikolesnikov2012@gmail.com
蒙古, Ulan-Bator
L. Stepanenko
Irkutsk State Medical University
Email: sikolesnikov2012@gmail.com
俄罗斯联邦, Irkutsk
O. Ogarkov
Research Center of Problems of Family Health and Human Reproduction; Irkutsk State Medical Academy of Post-Graduate Education
Email: sikolesnikov2012@gmail.com
俄罗斯联邦, Irkutsk; Irkutsk
D. Nyamkhuu
National Center of Investigation of Infectious Diseases
Email: sikolesnikov2012@gmail.com
蒙古, Ulan-Bator
K. Aitov
Irkutsk State Medical University
Email: sikolesnikov2012@gmail.com
俄罗斯联邦, Irkutsk
P. Nyamdawa
National Center of Investigation of Infectious Diseases
Email: sikolesnikov2012@gmail.com
蒙古, Ulan-Bator
S. Kolesnikov
Research Center of Problems of Family Health and Human Reproduction
Email: sikolesnikov2012@gmail.com
俄罗斯联邦, Irkutsk
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