Population Polymorphism of IFNL3 and IFNL4 Genes of Type 3 Interferon Associated with Spontaneous Clearance of Hepatitis C Virus in Representatives of Caucasian and Mongoloid Races
- Autores: Malov I.1, Malov S.1, Savilov E.2,3, Gantulga D.4, Stepanenko L.1, Ogarkov O.2,3, Nyamkhuu D.4, Aitov K.1, Nyamdawa P.4, Kolesnikov S.2
-
Afiliações:
- Irkutsk State Medical University
- Research Center of Problems of Family Health and Human Reproduction
- Irkutsk State Medical Academy of Post-Graduate Education
- National Center of Investigation of Infectious Diseases
- Edição: Volume 161, Nº 3 (2016)
- Páginas: 404-407
- Seção: Virology
- URL: https://journals.rcsi.science/0007-4888/article/view/237463
- DOI: https://doi.org/10.1007/s10517-016-3425-z
- ID: 237463
Citar
Resumo
The frequency of single nucleotide polymorphisms of IFNL3 gene (rsl12979860 and rs8099917) and dinucleotide polymorphism of IFNL4 gene (ss469415590) were estimated in healthy inhabitants of Mongolia and Irkutsk regions taking into account their races. Population and genetic studies were performed in 1520 conventionally healthy volunteers (blood donors), representatives of Caucasian and Mongoloid races. Significant race-related differences in the incidence of IFNL3 and IFNL4 gene polymorphisms associated with spontaneous clearance of hepatitis C virus were found in healthy volunteers.
Sobre autores
I. Malov
Irkutsk State Medical University
Email: sikolesnikov2012@gmail.com
Rússia, Irkutsk
S. Malov
Irkutsk State Medical University
Autor responsável pela correspondência
Email: sikolesnikov2012@gmail.com
Rússia, Irkutsk
E. Savilov
Research Center of Problems of Family Health and Human Reproduction; Irkutsk State Medical Academy of Post-Graduate Education
Email: sikolesnikov2012@gmail.com
Rússia, Irkutsk; Irkutsk
D. Gantulga
National Center of Investigation of Infectious Diseases
Email: sikolesnikov2012@gmail.com
Mongólia, Ulan-Bator
L. Stepanenko
Irkutsk State Medical University
Email: sikolesnikov2012@gmail.com
Rússia, Irkutsk
O. Ogarkov
Research Center of Problems of Family Health and Human Reproduction; Irkutsk State Medical Academy of Post-Graduate Education
Email: sikolesnikov2012@gmail.com
Rússia, Irkutsk; Irkutsk
D. Nyamkhuu
National Center of Investigation of Infectious Diseases
Email: sikolesnikov2012@gmail.com
Mongólia, Ulan-Bator
K. Aitov
Irkutsk State Medical University
Email: sikolesnikov2012@gmail.com
Rússia, Irkutsk
P. Nyamdawa
National Center of Investigation of Infectious Diseases
Email: sikolesnikov2012@gmail.com
Mongólia, Ulan-Bator
S. Kolesnikov
Research Center of Problems of Family Health and Human Reproduction
Email: sikolesnikov2012@gmail.com
Rússia, Irkutsk
![](/img/style/loading.gif)