Population Polymorphism of IFNL3 and IFNL4 Genes of Type 3 Interferon Associated with Spontaneous Clearance of Hepatitis C Virus in Representatives of Caucasian and Mongoloid Races
- Авторлар: Malov I.1, Malov S.1, Savilov E.2,3, Gantulga D.4, Stepanenko L.1, Ogarkov O.2,3, Nyamkhuu D.4, Aitov K.1, Nyamdawa P.4, Kolesnikov S.2
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Мекемелер:
- Irkutsk State Medical University
- Research Center of Problems of Family Health and Human Reproduction
- Irkutsk State Medical Academy of Post-Graduate Education
- National Center of Investigation of Infectious Diseases
- Шығарылым: Том 161, № 3 (2016)
- Беттер: 404-407
- Бөлім: Virology
- URL: https://journals.rcsi.science/0007-4888/article/view/237463
- DOI: https://doi.org/10.1007/s10517-016-3425-z
- ID: 237463
Дәйексөз келтіру
Аннотация
The frequency of single nucleotide polymorphisms of IFNL3 gene (rsl12979860 and rs8099917) and dinucleotide polymorphism of IFNL4 gene (ss469415590) were estimated in healthy inhabitants of Mongolia and Irkutsk regions taking into account their races. Population and genetic studies were performed in 1520 conventionally healthy volunteers (blood donors), representatives of Caucasian and Mongoloid races. Significant race-related differences in the incidence of IFNL3 and IFNL4 gene polymorphisms associated with spontaneous clearance of hepatitis C virus were found in healthy volunteers.
Авторлар туралы
I. Malov
Irkutsk State Medical University
Email: sikolesnikov2012@gmail.com
Ресей, Irkutsk
S. Malov
Irkutsk State Medical University
Хат алмасуға жауапты Автор.
Email: sikolesnikov2012@gmail.com
Ресей, Irkutsk
E. Savilov
Research Center of Problems of Family Health and Human Reproduction; Irkutsk State Medical Academy of Post-Graduate Education
Email: sikolesnikov2012@gmail.com
Ресей, Irkutsk; Irkutsk
D. Gantulga
National Center of Investigation of Infectious Diseases
Email: sikolesnikov2012@gmail.com
Моңғолия, Ulan-Bator
L. Stepanenko
Irkutsk State Medical University
Email: sikolesnikov2012@gmail.com
Ресей, Irkutsk
O. Ogarkov
Research Center of Problems of Family Health and Human Reproduction; Irkutsk State Medical Academy of Post-Graduate Education
Email: sikolesnikov2012@gmail.com
Ресей, Irkutsk; Irkutsk
D. Nyamkhuu
National Center of Investigation of Infectious Diseases
Email: sikolesnikov2012@gmail.com
Моңғолия, Ulan-Bator
K. Aitov
Irkutsk State Medical University
Email: sikolesnikov2012@gmail.com
Ресей, Irkutsk
P. Nyamdawa
National Center of Investigation of Infectious Diseases
Email: sikolesnikov2012@gmail.com
Моңғолия, Ulan-Bator
S. Kolesnikov
Research Center of Problems of Family Health and Human Reproduction
Email: sikolesnikov2012@gmail.com
Ресей, Irkutsk