Cytokine Profile in Experimental Models of Critical Limb Ischemia in Rats
- Авторы: Lykov A.1,2, Bondarenko N.1,2, Poveshchenko O.1,2, Kabakov A.1, Surovtseva M.1,2, Kim I.1,2, Kazakov O.1, Poveshchenko A.1,2, Yankaite E.1
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Учреждения:
- Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
- Выпуск: Том 168, № 1 (2019)
- Страницы: 150-155
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/242307
- DOI: https://doi.org/10.1007/s10517-019-04666-y
- ID: 242307
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Аннотация
We studied the effect of intramuscular administration of a cellular product (mesenchymal stem cells, conditioned media, and erythropoietin) on cytokine levels in blood serum, conditioned media of bone marrow mononuclears, and calf muscles in Wistar rats with hind limb ischemia. It is shown that the cellular product reduces the proinflammatory background at the early stages of the experiment and increases the content proangiogenic factors.
Об авторах
A. Lykov
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: aplykov2@mail.ru
Россия, Novosibirsk; Novosibirsk
N. Bondarenko
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Россия, Novosibirsk; Novosibirsk
O. Poveshchenko
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Россия, Novosibirsk; Novosibirsk
A. Kabakov
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Россия, Novosibirsk
M. Surovtseva
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Россия, Novosibirsk; Novosibirsk
I. Kim
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Россия, Novosibirsk; Novosibirsk
O. Kazakov
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Россия, Novosibirsk
A. Poveshchenko
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Россия, Novosibirsk; Novosibirsk
E. Yankaite
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Россия, Novosibirsk
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