Enviar artigo por via de e-mail Cytokine Profile in Experimental Models of Critical Limb Ischemia in Rats
- Autores: Lykov A.1,2, Bondarenko N.1,2, Poveshchenko O.1,2, Kabakov A.1, Surovtseva M.1,2, Kim I.1,2, Kazakov O.1, Poveshchenko A.1,2, Yankaite E.1
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Afiliações:
- Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
- Edição: Volume 168, Nº 1 (2019)
- Páginas: 150-155
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/242307
- DOI: https://doi.org/10.1007/s10517-019-04666-y
- ID: 242307
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Resumo
We studied the effect of intramuscular administration of a cellular product (mesenchymal stem cells, conditioned media, and erythropoietin) on cytokine levels in blood serum, conditioned media of bone marrow mononuclears, and calf muscles in Wistar rats with hind limb ischemia. It is shown that the cellular product reduces the proinflammatory background at the early stages of the experiment and increases the content proangiogenic factors.
Sobre autores
A. Lykov
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk
N. Bondarenko
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk
O. Poveshchenko
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk
A. Kabakov
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Rússia, Novosibirsk
M. Surovtseva
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk
I. Kim
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk
O. Kazakov
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Rússia, Novosibirsk
A. Poveshchenko
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk
E. Yankaite
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Rússia, Novosibirsk
