Cytokine Profile in Experimental Models of Critical Limb Ischemia in Rats
- Авторлар: Lykov A.1,2, Bondarenko N.1,2, Poveshchenko O.1,2, Kabakov A.1, Surovtseva M.1,2, Kim I.1,2, Kazakov O.1, Poveshchenko A.1,2, Yankaite E.1
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Мекемелер:
- Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
- Шығарылым: Том 168, № 1 (2019)
- Беттер: 150-155
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/242307
- DOI: https://doi.org/10.1007/s10517-019-04666-y
- ID: 242307
Дәйексөз келтіру
Аннотация
We studied the effect of intramuscular administration of a cellular product (mesenchymal stem cells, conditioned media, and erythropoietin) on cytokine levels in blood serum, conditioned media of bone marrow mononuclears, and calf muscles in Wistar rats with hind limb ischemia. It is shown that the cellular product reduces the proinflammatory background at the early stages of the experiment and increases the content proangiogenic factors.
Авторлар туралы
A. Lykov
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Хат алмасуға жауапты Автор.
Email: aplykov2@mail.ru
Ресей, Novosibirsk; Novosibirsk
N. Bondarenko
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Ресей, Novosibirsk; Novosibirsk
O. Poveshchenko
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Ресей, Novosibirsk; Novosibirsk
A. Kabakov
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Ресей, Novosibirsk
M. Surovtseva
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Ресей, Novosibirsk; Novosibirsk
I. Kim
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Ресей, Novosibirsk; Novosibirsk
O. Kazakov
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Ресей, Novosibirsk
A. Poveshchenko
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences; E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation
Email: aplykov2@mail.ru
Ресей, Novosibirsk; Novosibirsk
E. Yankaite
Research Institute of Clinical and Experimental Lymphology, Branch of the Federal Research Center Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Ресей, Novosibirsk