Отправить статью по E-mail Effect of Stimulation of α2-Adrenergic Receptors on Action Potential of Working Cardiomyocytes in Rat Atrium
- Авторы: Zefirov T.1, Faskhutdinov L.1, Ziyatdinova N.1, Galieva A.1, Zefirov A.2
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Учреждения:
- Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
- Department of Normal Physiology, Kazan State Medical University
- Выпуск: Том 167, № 5 (2019)
- Страницы: 603-605
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/241954
- DOI: https://doi.org/10.1007/s10517-019-04579-w
- ID: 241954
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Аннотация
The study examined the effect of clonidine hydrochloride (10—9-10—5 М) on electrical activity of working cardiomyocytes in rat right atrium. Stimulation of α2-adrenergic receptor with clonidine changed electrical activity of the heart. All tested concentrations of the agonist lengthened the action potential and decreased the firing rate of cardiomyocytes in a dose-dependent manner. The maximum effects of clonidine were observed at concentration of 10—5 М.
Об авторах
T. Zefirov
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Автор, ответственный за переписку.
Email: zefirovtl@mail.ru
Россия, Kazan
L. Faskhutdinov
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
Россия, Kazan
N. Ziyatdinova
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
Россия, Kazan
A. Galieva
Department of Anatomy, Physiology, and Human Health Protection, Kazan Federal University
Email: zefirovtl@mail.ru
Россия, Kazan
A. Zefirov
Department of Normal Physiology, Kazan State Medical University
Email: zefirovtl@mail.ru
Россия, Kazan, Republic of Tatarstan
