Отправить статью по E-mail Reinforced Hybrid Collagen Sponges for Tissue Engineering
- Авторы: Bardakova K.1,2, Grebenik E.2, Istranova E.2, Istranov L.2, Gerasimov Y.3, Grosheva A.3, Zharikova T.2, Minaev N.1, Shavkuta B.1,2, Dudova D.1, Kostyuk S.4, Vorob’eva N.1, Bagratashvili V.1, Timashev P.1,2, Chailakhyan R.1,3
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Учреждения:
- Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
- Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
- N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
- Research Institute for Physical Chemical Problems, Belarusian State University
- Выпуск: Том 165, № 1 (2018)
- Страницы: 142-147
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240068
- DOI: https://doi.org/10.1007/s10517-018-4116-8
- ID: 240068
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Аннотация
We created an anisotropic material based on collagen sponge and reactive polylactide structured by laser photopolymerization. The combination of collagen with reactive polylactide improves the resistance of the formed matrices to biodegradation in comparison with collagen sponge, while the existence of sites with different mechanical characteristics and cell affinity on the matrix provides directed cell growth during their culturing. It was shown that reinforcement of the collagen sponges 7-fold increased the mean Young’s modulus for the hybrid matrix without affecting its cytotoxicity. The developed matrix provides cell adhesion and proliferation along reinforcement lines and can be used for fabrication of tissue engineering constructs.
Об авторах
K. Bardakova
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Россия, Moscow; Moscow
E. Grebenik
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Россия, Moscow
E. Istranova
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Россия, Moscow
L. Istranov
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Россия, Moscow
Yu. Gerasimov
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Россия, Moscow
A. Grosheva
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Россия, Moscow
T. Zharikova
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Россия, Moscow
N. Minaev
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Россия, Moscow
B. Shavkuta
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Россия, Moscow; Moscow
D. Dudova
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Россия, Moscow
S. Kostyuk
Research Institute for Physical Chemical Problems, Belarusian State University
Email: rubenchail@yandex.ru
Белоруссия, Minsk
N. Vorob’eva
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Россия, Moscow
V. Bagratashvili
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Россия, Moscow
P. Timashev
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Россия, Moscow; Moscow
R. Chailakhyan
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Автор, ответственный за переписку.
Email: rubenchail@yandex.ru
Россия, Moscow; Moscow
