Enviar artigo por via de e-mail Reinforced Hybrid Collagen Sponges for Tissue Engineering
- Autores: Bardakova K.1,2, Grebenik E.2, Istranova E.2, Istranov L.2, Gerasimov Y.3, Grosheva A.3, Zharikova T.2, Minaev N.1, Shavkuta B.1,2, Dudova D.1, Kostyuk S.4, Vorob’eva N.1, Bagratashvili V.1, Timashev P.1,2, Chailakhyan R.1,3
-
Afiliações:
- Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
- Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
- N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
- Research Institute for Physical Chemical Problems, Belarusian State University
- Edição: Volume 165, Nº 1 (2018)
- Páginas: 142-147
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240068
- DOI: https://doi.org/10.1007/s10517-018-4116-8
- ID: 240068
Citar
Acesso aberto
Acesso está concedido
Somente assinantes
Resumo
We created an anisotropic material based on collagen sponge and reactive polylactide structured by laser photopolymerization. The combination of collagen with reactive polylactide improves the resistance of the formed matrices to biodegradation in comparison with collagen sponge, while the existence of sites with different mechanical characteristics and cell affinity on the matrix provides directed cell growth during their culturing. It was shown that reinforcement of the collagen sponges 7-fold increased the mean Young’s modulus for the hybrid matrix without affecting its cytotoxicity. The developed matrix provides cell adhesion and proliferation along reinforcement lines and can be used for fabrication of tissue engineering constructs.
Sobre autores
K. Bardakova
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow; Moscow
E. Grebenik
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
E. Istranova
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
L. Istranov
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
Yu. Gerasimov
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
A. Grosheva
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
T. Zharikova
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow
N. Minaev
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Rússia, Moscow
B. Shavkuta
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow; Moscow
D. Dudova
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Rússia, Moscow
S. Kostyuk
Research Institute for Physical Chemical Problems, Belarusian State University
Email: rubenchail@yandex.ru
Belarus, Minsk
N. Vorob’eva
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Rússia, Moscow
V. Bagratashvili
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Rússia, Moscow
P. Timashev
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Rússia, Moscow; Moscow
R. Chailakhyan
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Autor responsável pela correspondência
Email: rubenchail@yandex.ru
Rússia, Moscow; Moscow
