Effect of Intramuscular Administration of Mesenchymal Stem Cells and Erythropoietin on Angiogenesis in Critical Limb Ischemia
- Авторы: Lykov A.1, Bondarenko N.1, Poveshchenko O.1, Kabakov A.1, Surovtseva M.1, Kim I.1, Kazakov O.1, Poveshchenko A.1
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Учреждения:
- Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- Выпуск: Том 165, № 1 (2018)
- Страницы: 121-126
- Раздел: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240042
- DOI: https://doi.org/10.1007/s10517-018-4112-z
- ID: 240042
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Аннотация
We studied the effect of intramuscular injections of bone marrow mesenchymal stromal cells on microcirculation parameters in an ischemic limb of Wistar rats. It was shown that transplantation of mesenchymal stem cells with or without erythropoietin stimulates angiogenesis in the ischemic zone. An essential role in angiogenesis stimulation is played by cytokines and growth factors.
Об авторах
A. Lykov
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Автор, ответственный за переписку.
Email: aplykov2@mail.ru
Россия, Novosibirsk
N. Bondarenko
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Россия, Novosibirsk
O. Poveshchenko
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Россия, Novosibirsk
A. Kabakov
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Россия, Novosibirsk
M. Surovtseva
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Россия, Novosibirsk
I. Kim
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Россия, Novosibirsk
O. Kazakov
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Россия, Novosibirsk
A. Poveshchenko
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Россия, Novosibirsk
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