Enviar artigo por via de e-mail Effect of Intramuscular Administration of Mesenchymal Stem Cells and Erythropoietin on Angiogenesis in Critical Limb Ischemia
- Autores: Lykov A.1, Bondarenko N.1, Poveshchenko O.1, Kabakov A.1, Surovtseva M.1, Kim I.1, Kazakov O.1, Poveshchenko A.1
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Afiliações:
- Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- Edição: Volume 165, Nº 1 (2018)
- Páginas: 121-126
- Seção: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240042
- DOI: https://doi.org/10.1007/s10517-018-4112-z
- ID: 240042
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Resumo
We studied the effect of intramuscular injections of bone marrow mesenchymal stromal cells on microcirculation parameters in an ischemic limb of Wistar rats. It was shown that transplantation of mesenchymal stem cells with or without erythropoietin stimulates angiogenesis in the ischemic zone. An essential role in angiogenesis stimulation is played by cytokines and growth factors.
Sobre autores
A. Lykov
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Autor responsável pela correspondência
Email: aplykov2@mail.ru
Rússia, Novosibirsk
N. Bondarenko
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Rússia, Novosibirsk
O. Poveshchenko
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Rússia, Novosibirsk
A. Kabakov
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Rússia, Novosibirsk
M. Surovtseva
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Rússia, Novosibirsk
I. Kim
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Rússia, Novosibirsk
O. Kazakov
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Rússia, Novosibirsk
A. Poveshchenko
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Rússia, Novosibirsk
