Effect of Intramuscular Administration of Mesenchymal Stem Cells and Erythropoietin on Angiogenesis in Critical Limb Ischemia
- Авторлар: Lykov A.1, Bondarenko N.1, Poveshchenko O.1, Kabakov A.1, Surovtseva M.1, Kim I.1, Kazakov O.1, Poveshchenko A.1
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Мекемелер:
- Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- Шығарылым: Том 165, № 1 (2018)
- Беттер: 121-126
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240042
- DOI: https://doi.org/10.1007/s10517-018-4112-z
- ID: 240042
Дәйексөз келтіру
Аннотация
We studied the effect of intramuscular injections of bone marrow mesenchymal stromal cells on microcirculation parameters in an ischemic limb of Wistar rats. It was shown that transplantation of mesenchymal stem cells with or without erythropoietin stimulates angiogenesis in the ischemic zone. An essential role in angiogenesis stimulation is played by cytokines and growth factors.
Авторлар туралы
A. Lykov
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Хат алмасуға жауапты Автор.
Email: aplykov2@mail.ru
Ресей, Novosibirsk
N. Bondarenko
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Ресей, Novosibirsk
O. Poveshchenko
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Ресей, Novosibirsk
A. Kabakov
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Ресей, Novosibirsk
M. Surovtseva
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Ресей, Novosibirsk
I. Kim
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Ресей, Novosibirsk
O. Kazakov
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Ресей, Novosibirsk
A. Poveshchenko
Research Institute of Clinical and Experimental Lymphology —Branch of Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Ресей, Novosibirsk