Effect of Polyethylene Terephthalate on Functional Properties of Endothelial and Mesenchymal Cells


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Resumo

We studied the influence of vascular prostheses made of polytetrafluoroethylene and polyethylene terephthalate on the proliferation, migration, and NO production by bone marrow mesenchymal stem cells, human endothelial progenitor cells, and EA.hy926 endothelial cells, colonization of the prosthesis surface by endothelial and mesenchymal cells was also analyzed. Synthetic prostheses have a negative effect on cell proliferation and migration, while surface treatment with proteins (fibronectin or gelatin) promotes colonization of the prostheses with cells.

Sobre autores

A. Lykov

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Autor responsável pela correspondência
Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk

O. Poveshchenko

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk

M. Surovtseva

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk

N. Bondarenko

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk

I. Kim

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
Rússia, Novosibirsk; Novosibirsk

A. Karpenko

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
Rússia, Novosibirsk

E. Pokushalov

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
Rússia, Novosibirsk

A. Karaskov

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
Rússia, Novosibirsk


Declaração de direitos autorais © Springer Science+Business Media, LLC, part of Springer Nature, 2019

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