Email this article Effect of Polyethylene Terephthalate on Functional Properties of Endothelial and Mesenchymal Cells
- Authors: Lykov A.P.1,2, Poveshchenko O.V.1,2, Surovtseva M.A.1,2, Bondarenko N.A.1,2, Kim I.I.1,2, Karpenko A.A.1, Pokushalov E.A.1, Karaskov A.M.1
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Affiliations:
- E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences
- Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
- Issue: Vol 166, No 4 (2019)
- Pages: 580-585
- Section: Translated from Kletochnye Tekhnologii v Biologii i Meditsine (Cell Technologies in Biology and Medicine)
- URL: https://journals.rcsi.science/0007-4888/article/view/241205
- DOI: https://doi.org/10.1007/s10517-019-04395-2
- ID: 241205
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Abstract
We studied the influence of vascular prostheses made of polytetrafluoroethylene and polyethylene terephthalate on the proliferation, migration, and NO production by bone marrow mesenchymal stem cells, human endothelial progenitor cells, and EA.hy926 endothelial cells, colonization of the prosthesis surface by endothelial and mesenchymal cells was also analyzed. Synthetic prostheses have a negative effect on cell proliferation and migration, while surface treatment with proteins (fibronectin or gelatin) promotes colonization of the prostheses with cells.
About the authors
A. P. Lykov
E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Author for correspondence.
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
O. V. Poveshchenko
E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
M. A. Surovtseva
E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
N. A. Bondarenko
E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
I. I. Kim
E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk; Novosibirsk
A. A. Karpenko
E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk
E. A. Pokushalov
E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk
A. M. Karaskov
E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences
Email: aplykov2@mail.ru
Russian Federation, Novosibirsk
