Effect of Polyethylene Terephthalate on Functional Properties of Endothelial and Mesenchymal Cells


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We studied the influence of vascular prostheses made of polytetrafluoroethylene and polyethylene terephthalate on the proliferation, migration, and NO production by bone marrow mesenchymal stem cells, human endothelial progenitor cells, and EA.hy926 endothelial cells, colonization of the prosthesis surface by endothelial and mesenchymal cells was also analyzed. Synthetic prostheses have a negative effect on cell proliferation and migration, while surface treatment with proteins (fibronectin or gelatin) promotes colonization of the prostheses with cells.

作者简介

A. Lykov

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

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Email: aplykov2@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk

O. Poveshchenko

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk

M. Surovtseva

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk

N. Bondarenko

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk

I. Kim

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences; Research Institute of Clinical and Experimental Lymphology, Affiliated Branch of the Federal Research Centre Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
俄罗斯联邦, Novosibirsk; Novosibirsk

A. Karpenko

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
俄罗斯联邦, Novosibirsk

E. Pokushalov

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
俄罗斯联邦, Novosibirsk

A. Karaskov

E. N. Meshalkin National Medical Research Center, Ministry of Health of the Russian Federation, Siberian Division of the Russian Academy of Sciences

Email: aplykov2@mail.ru
俄罗斯联邦, Novosibirsk


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