Reinforced Hybrid Collagen Sponges for Tissue Engineering
- Авторлар: Bardakova K.1,2, Grebenik E.2, Istranova E.2, Istranov L.2, Gerasimov Y.3, Grosheva A.3, Zharikova T.2, Minaev N.1, Shavkuta B.1,2, Dudova D.1, Kostyuk S.4, Vorob’eva N.1, Bagratashvili V.1, Timashev P.1,2, Chailakhyan R.1,3
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Мекемелер:
- Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
- Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
- N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
- Research Institute for Physical Chemical Problems, Belarusian State University
- Шығарылым: Том 165, № 1 (2018)
- Беттер: 142-147
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240068
- DOI: https://doi.org/10.1007/s10517-018-4116-8
- ID: 240068
Дәйексөз келтіру
Аннотация
We created an anisotropic material based on collagen sponge and reactive polylactide structured by laser photopolymerization. The combination of collagen with reactive polylactide improves the resistance of the formed matrices to biodegradation in comparison with collagen sponge, while the existence of sites with different mechanical characteristics and cell affinity on the matrix provides directed cell growth during their culturing. It was shown that reinforcement of the collagen sponges 7-fold increased the mean Young’s modulus for the hybrid matrix without affecting its cytotoxicity. The developed matrix provides cell adhesion and proliferation along reinforcement lines and can be used for fabrication of tissue engineering constructs.
Авторлар туралы
K. Bardakova
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow; Moscow
E. Grebenik
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow
E. Istranova
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow
L. Istranov
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow
Yu. Gerasimov
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow
A. Grosheva
N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow
T. Zharikova
Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow
N. Minaev
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Ресей, Moscow
B. Shavkuta
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow; Moscow
D. Dudova
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Ресей, Moscow
S. Kostyuk
Research Institute for Physical Chemical Problems, Belarusian State University
Email: rubenchail@yandex.ru
Белоруссия, Minsk
N. Vorob’eva
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Ресей, Moscow
V. Bagratashvili
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences
Email: rubenchail@yandex.ru
Ресей, Moscow
P. Timashev
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; Institute of Regenerative Medicine, I. M. Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation
Email: rubenchail@yandex.ru
Ресей, Moscow; Moscow
R. Chailakhyan
Institute of Photonics Technologies, Federal Research Centre “Crystallography and Photonics”, Russian Academy of Sciences; N. F. Gamaleya National Research Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Хат алмасуға жауапты Автор.
Email: rubenchail@yandex.ru
Ресей, Moscow; Moscow