Мақаланы E-mail арқылы жіберу Glycolysis Inhibitors Monoiodoacetate and 2-Deoxyglucose as Antitumor Agents: Experimental Study on Lewis Lung Carcinoma Model
- Авторлар: Korshunov D.1, Klimov I.2, Ivanov V.2, Kondakova I.1
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Мекемелер:
- Research Institute of Oncology, Tomsk Natinoal Research Medical Center, Russian Academy of Sciences, Ministry of Health of Russia
- Laboratory of Biological Models, Siberian State Medical University, Ministry of Health of Russia
- Шығарылым: Том 165, № 5 (2018)
- Беттер: 695-697
- Бөлім: Article
- URL: https://journals.rcsi.science/0007-4888/article/view/240685
- DOI: https://doi.org/10.1007/s10517-018-4244-1
- ID: 240685
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
Тек жазылушылар үшін
Аннотация
Antitumor effects of glycolysis inhibitors monoiodoacetate and 2-deoxyglucose were studied on Lewis lung carcinoma model. Monoiodoacetate exhibited antitumor and antimetastatic activities, being not inferior of methotrexate (reference drug); however, the preparation also demonstrated high systemic toxicity. 2-Deoxyglucose exhibited only antitumor effect, while its antimetastatic activity did not differ from the result in the group without treatment.
Авторлар туралы
D. Korshunov
Research Institute of Oncology, Tomsk Natinoal Research Medical Center, Russian Academy of Sciences, Ministry of Health of Russia
Хат алмасуға жауапты Автор.
Email: ieved@ya.ru
Ресей, Tomsk
I. Klimov
Laboratory of Biological Models, Siberian State Medical University, Ministry of Health of Russia
Email: ieved@ya.ru
Ресей, Tomsk
V. Ivanov
Laboratory of Biological Models, Siberian State Medical University, Ministry of Health of Russia
Email: ieved@ya.ru
Ресей, Tomsk
I. Kondakova
Research Institute of Oncology, Tomsk Natinoal Research Medical Center, Russian Academy of Sciences, Ministry of Health of Russia
Email: ieved@ya.ru
Ресей, Tomsk
