Мақаланы E-mail арқылы жіберу Effects of Glycolipid Rhodococcus Biosurfactant on Innate and Adaptive Immunity Parameters In Vivo
- Авторлар: Gein S.1,2, Kochina O.1, Kuyukina M.1,2, Ivshina I.1,2
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Мекемелер:
- Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences
- Perm State National Research University
- Шығарылым: Том 165, № 3 (2018)
- Беттер: 368-372
- Бөлім: Immunology and Microbiology
- URL: https://journals.rcsi.science/0007-4888/article/view/240313
- DOI: https://doi.org/10.1007/s10517-018-4172-0
- ID: 240313
Дәйексөз келтіру
Ашық рұқсат
Рұқсат берілді
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Аннотация
The glycolipid biosurfactant complex from actinobacterium Rhodococcus ruber IEGM 231 inhibits the innate and adaptive immunity parameters after intraperitoneal and intramuscular injection. Marked suppression of antibody production, bactericidal potential, and production of proinflammatory cytokines by peritoneal macrophages, detected in vivo, do not agree with the previously detected immunostimulatory activity of biosurfactants towards the immunocompetent cell cultures; this fact indicates an important role of the cell environment in the formation of immune response under the effect of bacterial glycolipids.
Авторлар туралы
S. Gein
Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences; Perm State National Research University
Хат алмасуға жауапты Автор.
Email: gein@iegm.ru
Ресей, Perm; Perm
O. Kochina
Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences
Email: gein@iegm.ru
Ресей, Perm
M. Kuyukina
Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences; Perm State National Research University
Email: gein@iegm.ru
Ресей, Perm; Perm
I. Ivshina
Institute of Ecology and Genetics of Microorganisms, Ural Division of the Russian Academy of Sciences; Perm State National Research University
Email: gein@iegm.ru
Ресей, Perm; Perm
